MOTIVATION: Analysis of whole-genome sequencing (WGS) for genetics is still a challenge due to the lack of accurate functional annotation of non-coding variants, especially the rare ones. As eQTLs have been extensively implicated in the genetics of h...
Graves disease (GD) and type 2 diabetes mellitus (T2DM) both impair liver function; we therefore explored the possibility of a relationship among diabetic control, thyroid function, and liver function. This retrospective, cross-sectional study compar...
Mathematical biosciences and engineering : MBE
Jul 18, 2022
Glucose management for people with type 2 diabetes mellitus is essential but challenging due to the multi-factored and chronic disease nature of diabetes. To control glucose levels in a safe range and lessen abnormal glucose variability efficiently a...
Journal of the American Medical Informatics Association : JAMIA
Jul 12, 2022
OBJECTIVE: People are increasingly encouraged to self-manage their chronic conditions; however, many struggle to practise it effectively. Most studies that investigate patient work (ie, tasks involved in self-management and contexts influencing such ...
Studies in health technology and informatics
May 25, 2022
Type 2 diabetes mellitus is a metabolic disorder of glucose management, whose prevalence is increasing inexorably worldwide. Adherence to therapies, along with a healthy lifestyle can help prevent the onset of disease. This preliminary study proposes...
Feature representation and discriminative learning are proven models and technologies in artificial intelligence fields; however, major challenges for machine learning on large biological datasets are learning an effective model with mechanistical ex...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2022
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has spread on an unprecedented scale around the globe. Despite of 141,975 published papers on COVID-19 and several hundreds of new studies carri...
BACKGROUND: The prevalence of type 2 diabetes has increased substantially in India over the past 3 decades. Undiagnosed diabetes presents a public health challenge, especially in rural areas, where access to laboratory testing for diagnosis may not b...
This work aims to explore risk factors for ischemic stroke in young adults and analyze the Traditional Vascular Risk Factors Model based on age, hypertension, diabetes, smoking history, and drinking history. Further, the Lipid Metabolism Model was an...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2021
OBJECTIVE: To present clinicians at the point-of-care with real-world data on the effectiveness of various treatment options in a precision cohort of patients closely matched to the index patient.
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