AIMC Topic: Drug Compounding
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Chitosan-tripolyphosphate nanoparticles: Optimization of formulation parameters for improving process yield at a novel pH using artificial neural networks.
International journal of biological macromolecules
Jan 16, 2016
At a novel pH value of the polymeric solution (6.2), variable chitosan (Cs) and sodium tripolyphosphate (TPP) concentrations and mass ratios were optimized to improve the process yield without undesirable particle flocculation. Prepared formulations ...
Preparation, Characterization, and Antitumor Activities of Miriplatin-Loaded Liposomes.
Journal of pharmaceutical sciences
Dec 22, 2015
Because of the insolubility of miriplatin in water, miriplatin and lipiodol suspension is the sole formulation of miriplatin approved in Japan to treat hepatocellular carcinoma by transcatheter arterial chemoembolization. Until now, there have been n...
Preparation, characterization and biocompatibility studies of thermoresponsive eyedrops based on the combination of nanostructured lipid carriers (NLC) and the polymer Pluronic F-127 for controlled delivery of ibuprofen.
Pharmaceutical development and technology
Dec 20, 2015
CONTEXT: Nanostructured lipid carrier (NLC) dispersions present low viscosity and poor mucoadhesive properties, which reduce the pre-corneal residence time and consequently, the bioavailability of ocular drugs.
A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Aug 5, 2015
The acceleration of solid dosage form product development can be facilitated by the inclusion of excipients that exhibit poly-/multi-functionality with reduction of the time invested in multiple excipient optimisations. Because active pharmaceutical ...
Porosity
Tablets
Drug Liberation
Powders
Algorithms
Computational Biology
Anti-Inflammatory Agents, Non-Steroidal
Surface Properties
Elasticity
Static Electricity
Tensile Strength
Expert Systems
Drug Compounding
Arginine
Microscopy, Electron, Scanning
Indomethacin
Statistics as Topic
Mechanical Phenomena
Excipients
Compressive Strength
[Implementation of a robot for the preparation of antineoplastic drugs in the Pharmacy Service].
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria
May 1, 2015
OBJECTIVE: To describe the implementation of a robot for the preparation of antineoplastic drugs in the Pharmacy Service and to be able to analyze the added value to pharmacotherapy.
Comparison of novel granulated pellet-containing tablets and traditional pellet-containing tablets by artificial neural networks.
Pharmaceutical development and technology
Apr 24, 2014
Novel granulated pellets technique was adopted to prepare granulated pellet-containing tablets (GPCT). GPCT and traditional pellet-containing tablets (PCT) were prepared according to 29 formulations devised by the Design Expert 7.0, with doxycycline ...
Environmental contamination, product contamination and workers exposure using a robotic system for antineoplastic drug preparation.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Feb 23, 2014
Environmental contamination, product contamination and technicians exposure were measured following preparation of iv bags with cyclophosphamide using the robotic system CytoCare. Wipe samples were taken inside CytoCare, in the clean room environment...
Gloves, Protective
Cyclophosphamide
Risk Factors
Antineoplastic Agents, Alkylating
Equipment Contamination
Pharmacy Service, Hospital
Risk Assessment
Drug Contamination
Occupational Exposure
Air Pollutants, Occupational
Environmental Monitoring
Environment, Controlled
Infusions, Intravenous
Humans
Robotics
Equipment Design
Drug Compounding
Application of rheology to hot melt extrusion: Theory and practice.
International journal of pharmaceutics
Jul 25, 2025
Hot melt extrusion (HME) has become a key manufacturing method in the pharmaceutical industry for developing novel drug delivery systems, due to its solvent-free nature, ease of operation, and ability to achieve one-step molding and continuous proces...
Advancing Amorphous Solid Dispersions Design: Insights into Dissolution Kinetics via Thermodynamic Descriptor and Machine Learning.
Molecular pharmaceutics
Jul 7, 2025
Amorphous solid dispersions (ASD) are an effective strategy for enhancing the solubility and bioavailability of poorly soluble drugs. However, designing and optimizing ASD formulations often rely on extensive dissolution experiments without sufficie...
Recent advancements of Raman spectroscopy application in topical products.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
Jul 1, 2025
Topical products have gained popularity in the recent years. Diverse formulation types, complex composition, and thermodynamically instable nature present great challenges in the formulation development of topical products. The analytical methods ava...
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