AIMC Topic: Drugs, Chinese Herbal

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Simultaneous Determination of Five Active Components in the Chinese Patent Medicine Niuhuang Jiangya Pill by HPLC-MS/MS.

Journal of AOAC International
Niuhuang Jiangya (NHJY) pill is one of the well-known Chinese patent medicines in China used in the treatment of high blood pressure. The primary purpose of this study was to establish and validate a method using HPLC with tandem MS for the quality e...

A rapid integrated bioactivity evaluation system based on near-infrared spectroscopy for quality control of Flos Chrysanthemi.

Journal of pharmaceutical and biomedical analysis
For quality control of herbal medicines or functional foods, integral activity evaluation has become more popular in recent studies. The majority of researchers focus on the relationship between chromatography/mass spectroscopy and bioactivity, but t...

ANTIOXIDANT ACTIVITY AND HEPATOPROTECTIVE EFFECTS OF COMPOUND .

African journal of traditional, complementary, and alternative medicines : AJTCAM
BACKGROUND: Chinese medicine has its own uniqueness, advantageous in the treatment of hepatic diseases, and they were widely used in the oxidation. At the same time, oxidation is one of the mechanism of protect liver.

Chinese Herbal Medicine Image Recognition and Retrieval by Convolutional Neural Network.

PloS one
Chinese herbal medicine image recognition and retrieval have great potential of practical applications. Several previous studies have focused on the recognition with hand-crafted image features, but there are two limitations in them. Firstly, most of...

Drug target identification using network analysis: Taking active components in Sini decoction as an example.

Scientific reports
Identifying the molecular targets for the beneficial effects of active small-molecule compounds simultaneously is an important and currently unmet challenge. In this study, we firstly proposed network analysis by integrating data from network pharmac...

Five-descriptor model to predict the chromatographic sequence of natural compounds.

Journal of separation science
Despite the recent introduction of mass detection techniques, ultraviolet detection is still widely applied in the field of the chromatographic analysis of natural medicines. Here, a neural network cascade model consisting of nine small artificial ne...

Effects of Shen-Fu injection on coagulation-fibrinolysis disorders in a porcine model of cardiac arrest.

The American journal of emergency medicine
OBJECTIVE: The objective of the study is to investigate the effects of Shen-Fu injection (SFI) on coagulation-fibrinolysis disorders in a porcine model of cardiac arrest.

Simultaneous determination and pharmacokinetics of five alkaloids in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry after the oral administration of Corydalis bungeana Turcz extract.

Journal of separation science
Pharmacokinetic studies were conducted on rats for protopine, corynoline, 7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl)-ethyl]propenamide, acetylcorynoline, and 8-oxocorynoline, five main active components from Corydalis bungeana Turcz (C. bungeana...

Danhong huayu koufuye prevents deep vein thrombosis through anti-inflammation in rats.

The Journal of surgical research
BACKGROUND: Danhong huayu koufuye (DHK) has traditionally been used clinically for a long time in China. This study was to evaluate the effect of DHK in treating deep vein thrombosis (DVT) in rats and explore its possible mechanism.