AIMC Topic: Epithelial Cells

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Quantitative scoring of epithelial and mesenchymal qualities of cancer cells using machine learning and quantitative phase imaging.

Journal of biomedical optics Feb 1, 2020
SIGNIFICANCE: We introduce an application of machine learning trained on optical phase features of epithelial and mesenchymal cells to grade cancer cells' morphologies, relevant to evaluation of cancer phenotype in screening assays and clinical biops...
Breast Neoplasms Fibroblasts Algorithms Female Mesenchymal Stem Cells Holography Gingiva Epithelial Cells MCF-7 Cells Humans Machine Learning
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In vitro study of the nephrotoxicity of total Dahuang (Radix Et Rhizoma Rhei Palmati) anthraquinones and emodin in monolayer human proximal tubular epithelial cells cultured in a transwell chamber.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan Oct 1, 2019
OBJECTIVE: To examine changes in the morphology and physiological functions of human proximal tubular epithelial cells (HK-2 cells) caused by total Dahuang (Radix Et Rhizoma Rhei Palmati) anthraquinones (TDA) and emodin.
Hepatitis A Virus Cellular Receptor 1 Kidney Tubules, Proximal Actins Emodin gamma-Glutamyltransferase L-Lactate Dehydrogenase Rheum Neoplasm Proteins Glucose Gene Expression Regulation Absorption, Physicochemical Anthraquinones Cell Line Epithelial Cells Humans Cell Proliferation
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[Toxicity of vehicle exhaust on BEAS-2B cells in vitro by air-liquid interface].

Wei sheng yan jiu = Journal of hygiene research Sep 1, 2017
OBJECTIVE: To evaluate the toxic effect of vehicle exhaust( VE) on lung epithelial cells by air-liquid interface( ALI) method in vitro, and analyze the different toxicity of VE after being treated with 0. 2 μm filter.
Vehicle Emissions Air Pollutants Particulate Matter Epithelial Cells Particle Size Humans Reactive Oxygen Species
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Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening.

Molecular bioSystems Jul 25, 2017
Human Flap endonuclease1 (FEN1) is an enzyme that is indispensable for DNA replication and repair processes and inhibition of its Flap cleavage activity results in increased cellular sensitivity to DNA damaging agents (cisplatin, temozolomide, MMS, e...
Colon Drug Discovery Humans Machine Learning Epithelial Cells Cell Survival Gene Expression Antineoplastic Agents Cell Line, Tumor Organ Specificity Naphthoquinones Flap Endonucleases HEK293 Cells Databases, Chemical Inhibitory Concentration 50 Enzyme Inhibitors
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[The Protective Effect of Inhibition of PARP-1 on Inflammation Induced by PM2.5 in Human Bronchial Epithelial Cell Line.].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Nov 1, 2016
OBJECTIVES: To explore whether the inhibition of poly ADP-ribose polymerase-1(PARP-1) could attenuated inflammation induced by fine particulate matter (PM2.5) in human bronchial epithelial cell line.
Humans Inflammation Epithelial Cells Nitric Oxide Transcription Factor RelA Poly (ADP-Ribose) Polymerase-1 Particulate Matter Nitric Oxide Synthase Type II
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[Oxidative stress and mitochondrion-related cell apoptosis in human bronchial epithelial 16HBE cells induced by silica dust].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases Nov 1, 2015
OBJECTIVE: To investigate oxidative stress and mitochondria-related cell apoptosis induced by silica dust in human normal bronchial epithelial 16HBE cells.
Silicon Dioxide bcl-2-Associated X Protein Proto-Oncogene Proteins c-bcl-2 L-Lactate Dehydrogenase Mitochondria Epithelial Cells Cell Survival Apoptosis Reactive Oxygen Species Humans Cells, Cultured Superoxide Dismutase Dust Oxidative Stress
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