Irritable bowel syndrome (IBS), a disorder of gut-brain interaction, is diagnosed using symptom-based Rome criteria. These criteria classify IBS patients into four subtypes in accordance to their stool patterns. However, whether this subtyping approa...
Microplastics are pervasive environmental pollutants, making human exposure unavoidable. Although previous studies have detected microplastics in human blood and feces, these investigations were limited by small sample sizes and key contributors to m...
The interplay between diet and gut microbiome composition is complex. Faecal metabolites, the end products of human and microbial metabolism, provide insights into these interactions. Here, we integrate faecal metabolomics, metagenomics, and habitual...
Gut dysbiosis and systemic inflammation are increasingly recognized in the pathogenesis of knee osteoarthritis (OA). While altered gut microbiota profiles have been reported, the link between specific microbial taxa and physical functioning in OA pat...
Beach water testing for fecal indicator bacteria (FIB) is a key element of public health protection for beachgoers. Because the process can be expensive and time-consuming, many beaches are infrequently monitored, putting the health of the public at ...
BACKGROUND: Gut microbiota (GM) predict responses to immune checkpoint inhibitors (ICIs) in patients with advanced lung cancer. However, its role in patients with locally advanced lung cancer undergoing chemoradiotherapy (CRT) combined with consolida...
BACKGROUND: Accurate staging is pivotal for tailoring treatment intensity, optimizing resource allocation, and improving long-term patient outcomes in IBD. The intestinal microbiota and transcriptional profiles emerge as critical determinants in IBD ...
Our study explores signatures for Crohn's disease (CD) and Ulcerative Colitis (UC) reflecting an interplay between the intestinal microbiota, systemic inflammation, and plasma bile acid homeostasis. For this, 1,257 individuals scheduled for colonosco...
The gut microbiota is profoundly influenced by dietary choices, with emerging evidence linking it to various health outcomes. Here, we investigate diet-microbiota associations using detailed temporal nutrition intake data captured through real-time f...
Maternal-offspring gut bacteriomes are closely linked to each other; however, the effects of the maternal diet have not been fully elucidated. This study aimed to determine the effect of administration of octanoate, a medium-chain fatty acid as a phy...
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