AIMC Topic: Feces

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Simplifying Diagnosis of Bile Acid Diarrhea With Clinical and Biochemical Measurements on Blood and Single Stool Sample.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
BACKGROUND & AIMS: Diagnosis of bile acid diarrhea (BAD) has been based on 48-hour fecal BA excretion; serum 7αC4 (C4) has been used to screen for BAD. Optimal diagnostic cutoffs for C4 and biochemical measurements in a single stool sample are unknow...

Fecal volatile organic compounds for colorectal cancer detection: A systematic review and meta-analysis.

Computers in biology and medicine
BACKGROUND: Background: Fecal volatile organic compound (VOC) analysis has emerged as a promising non-invasive tool for detecting colorectal cancer (CRC). Despite its reported high diagnostic accuracy, clinical adoption is hindered due to issues like...

Brassica microgreens shape gut microbiota and functional metabolite profiles in a species-related manner: A multi-omics approach following in vitro gastrointestinal digestion and large intestine fermentation.

Microbiological research
Brassicaceae microgreens constitute a novel and promising source of bioactive compounds, such as polyphenols and glucosinolates. In this work, an integrative computational approach was performed to decipher the interaction between bioaccessible micro...

Significant associations between high-risk sexual behaviors and enterotypes of gut microbiome in HIV-negative men who have sex with men.

mSphere
UNLABELLED: Gut microbiome of men who have sex with men (MSM) exhibits distinctive characteristics compared with general populations. The dysbiosis of the gut microbiome in MSM is also associated with the onset and evolution of HIV infection. Enterot...

Novel robotic tools used for the detection of faecal shedding of Escherichia coli resistant to critically important antimicrobials in healthy dogs.

Veterinary microbiology
Escherichia coli recovered from dogs with clinical conditions such as urinary tract infections are often used to assess populations for resistance to critically important antimicrobials (CIAs). Despite the potential importance of such strains, the nu...

Four Different Artificial Intelligence Models Logistic Regression to Enhance the Diagnostic Accuracy of Fecal Immunochemical Test in the Detection of Colorectal Carcinoma in a Screening Setting.

Anticancer research
BACKGROUND/AIM: This study aimed to evaluate the diagnostic accuracy (DA) of four artificial intelligence (AI) models compared to logistic regression (LR) in enhancing the performance of the fecal immunochemical test (FIT) for the detection of colore...

Development and validation of the Open-Source Automatic Bowel Preparation Scale.

Gastrointestinal endoscopy
BACKGROUND AND AIMS: Insufficient bowel preparation accounts for up to 42% of missed adenomas in colonoscopy. However, major analysis programs found no correlation between adenoma detection rate and the human-rated Boston Bowel Preparation Scale (BBP...

An oral norovirus vaccine generates mucosal immunity and reduces viral shedding in a phase 2 placebo-controlled challenge study.

Science translational medicine
There are currently no licensed vaccines for norovirus, a leading cause of epidemic and endemic gastroenteritis worldwide. Clinical advancement of promising vaccine candidates from phase 2 studies to phase 3 field trials has been hampered by the lack...

Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study.

Genome medicine
BACKGROUND: The microbiome of adolescents is poorly understood, as are factors influencing its composition. We aimed to describe the healthy adolescent microbiome and identify early-life and concurrent predictors of its composition.

Impact of Blastocystis carriage and colonization intensity on gut microbiota composition in a non-westernized rural population from Colombia.

PLoS neglected tropical diseases
BACKGROUND: The role of Blastocystis, a common intestinal parasitic protist of humans and other animals, in human health and disease remains elusive. Recent studies suggest a connection between Blastocystis colonization, healthier lifestyles, and hig...