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Mass spectrometry combined with machine learning identifies novel protein signatures as demonstrated with multisystem inflammatory syndrome in children.

Scientific reports
Rapid and accurate diagnosis of emerging inflammatory illnesses is challenging due to overlapping clinical features with existing conditions. We demonstrate an approach that integrates proteomic analysis with machine learning to identify diagnostic p...

Advancing sleep health equity through deep learning on large-scale nocturnal respiratory signals.

Nature communications
Sleep disorders affect billions globally, yet diagnostic access remains limited by healthcare resource constraints. Here, we develop a deep learning framework that analyzes respiratory signals for remote sleep health monitoring, trained on 15,785 nig...

Exploring Patient Perspectives, Engagement, and Output Quality in Doctor-Supervised Use of Artificial Intelligence During Informed Consent Consultation With ChatGPT and Retrieval Augmented Generation (RAG): Quantitative Exploratory Study.

Journal of medical Internet research
BACKGROUND: Comprehensive preoperative education is essential for optimizing outcomes and ensuring informed consent in patients undergoing total hip arthroplasty (THA). Emerging artificial intelligence (AI) tools, such as ChatGPT, offer scalable supp...

Global Adoption, Promotion, Impact, and Deployment of AI in Patient Care, Health Care Delivery, Management, and Health Care Systems Leadership: Cross-Sectional Survey.

Journal of medical Internet research
BACKGROUND: Artificial intelligence (AI) is increasingly being integrated into health care, offering a wide array of benefits. Current AI applications encompass patients' diagnosis, treatment, data mining, and more to enhance patient care and quality...

Interpretable Machine Learning Model for Predicting and Assessing the Risk of Diabetic Nephropathy: Prediction Model Study.

JMIR medical informatics
BACKGROUND: Diabetic nephropathy (DN), a severe complication of diabetes, is characterized by proteinuria, hypertension, and progressive renal function decline, potentially leading to end-stage renal disease. The International Diabetes Federation pro...

Development and Validation of an Extra Spindle Pole Bodies-like 1-Based Diagnostic and Prognostic Model for Hepatitis B Virus-Related Hepatocellular Carcinoma: Retrospective Cohort Study.

JMIR medical informatics
BACKGROUND: Early diagnosis of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) is challenging. Models that combine novel biomarkers with clinical features may improve both early diagnosis and risk stratification, but f...

EEG based classification of sleep cyclic alternating patterns using frequency driven forward ternary encoding.

Sleep & breathing = Schlaf & Atmung
PURPOSE: Cyclic alternating patterns (CAP) of sleep can be observed through electroencephalogram (EEG) signals. Analyzing CAP can provide valuable insights into different abnormalities relating to sleep. CAP comprises of two phases: A and B, characte...

Automated AI detection of thoracic aortic dissection on CT imaging.

European radiology experimental
BACKGROUND: Aortic dissection (AD) is a life-threatening condition. We developed an artificial intelligence (AI) algorithm capable of robust, accurate, and automated AD detection and sub-classification.

Gaining Brain Insights by Tapping into the Black Box: Linking Structural MRI Features to Age and Cognition using Shapley-Based Interpretation Methods.

Neuroinformatics
Global interpretability in machine learning holds great potential for extracting meaningful insights from neuroimaging data to improve our understanding of brain function. Although various approaches exist to identify key contributing features at bot...