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Machine learning technique-based four-autoantibody test for early detection of esophageal squamous cell carcinoma: a multicenter, retrospective study with a nested case-control study.

BMC medicine
BACKGROUND: Autoantibodies represent promising diagnostic blood-based biomarkers that may be generated prior to the first clinically detectable signs of cancers. In present study, we aimed to identify a novel optimized autoantibody panel with high di...

Constructing a neural network model based on tumor-infiltrating lymphocytes (TILs) to predict the survival of hepatocellular carcinoma patients.

PeerJ
BACKGROUND: Hepatocellular carcinoma (HCC) is the most common primary liver cancer worldwide, and early pathological diagnosis is crucial for formulating treatment plans. Despite the widespread attention to pathology in the treatment of HCC patients,...

An informed machine learning based environmental risk score for hypertension in European adults.

Artificial intelligence in medicine
BACKGROUND: The exposome framework seeks to unravel the cumulated effects of environmental exposures on health. However, existing methods struggle with challenges including multicollinearity, non-linearity and confounding. To address these limitation...

Cascade learning in multi-task encoder-decoder networks for concurrent bone segmentation and glenohumeral joint clinical assessment in shoulder CT scans.

Artificial intelligence in medicine
Osteoarthritis is a degenerative condition that affects bones and cartilage, often leading to structural changes, including osteophyte formation, bone density loss, and the narrowing of joint spaces. Over time, this process may disrupt the glenohumer...

Unraveling Parkinson's disease motor subtypes: A deep learning approach based on spatiotemporal dynamics of EEG microstates.

Neurobiology of disease
BACKGROUND: Despite prior studies on early-stage Parkinson's disease (PD) brain connectivity and temporal patterns, differences between tremor-dominant (TD) and postural instability/gait difficulty (PIGD) motor subtypes remain poorly understood. Our ...

Machine learning-based analysis on factors influencing blood heavy metal concentrations in the Korean CHildren's ENvironmental health Study (Ko-CHENS).

The Science of the total environment
Heavy metal concentration in pregnant women affects neurocognitive and behavioral development of their infants and children. The majority of existing research focusing on pregnant women's heavy metal concentration has considered individual environmen...

Machine learning to risk stratify chest pain patients with non-diagnostic electrocardiogram in an Asian emergency department.

Annals of the Academy of Medicine, Singapore
INTRODUCTION: Elevated troponin, while essential for diagnosing myocardial infarction, can also be present in non-myocardial infarction conditions. The myocardial-ischaemic-injury-index (MI3) algorithm is a machine learning algorithm that considers a...

Fast and effective assessment for individuals with special needs form optimization and prediction models.

BMC psychology
The aim of this study was to determine which items in the psychological assessment forms used by counselling and research centres for individuals with special needs are effective in classifying individuals into special needs diagnostic categories. Da...

A wearable ankle-assisted robot for improving gait function and pattern in stroke patients.

Journal of neuroengineering and rehabilitation
BACKGROUND: Hemiplegic gait after a stroke can result in a decreased gait speed and asymmetrical gait pattern. Normal gait patterns and speed are typically the ultimate goals of gait function in stroke rehabilitation. The purpose of this study was to...