AIMC Topic: Fluorescence

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Machine learning-assisted washing-free detection of extracellular vesicles by target recycling amplification based fluorescent aptasensor for accurate diagnosis of gastric cancer.

Talanta
Extracellular vesicles (EVs) are promising non-invasive biomarkers for cancer diagnosis. EVs proteins play a critical role in tumor progress and metastasis. However, accurately and reliably diagnosing cancers is greatly limited by single protein mark...

A Green Synchronous Fluorescence Analysis Approach for Simultaneous Determination of the Co-formulated Antihypertensives, Bisoprolol, and Amlodipine. Application to Plasma Samples, Market Formulations, Content Uniformity Test, and Greenness Evaluation.

Luminescence : the journal of biological and chemical luminescence
In this study, we present a direct, sensitive, and green spectrofluorimetric approach for simultaneous measurement of bisoprolol fumarate (BSL) and amlodipine besylate (AMD) in their tablets and plasma. This approach measures the synchronized fluores...

FMT-ReconNet: Fluorescence Molecular Tomography Reconstruction using Prior Knowledge and Deformation Neural Network.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Fluorescence molecular tomography (FMT) is a powerful imaging technique for 3D reconstruction of internal fluorescent sources. However, its spatial resolution is limited by a simplified forward model and an ill-posed inverse problem. To address this,...

Deep Learning for Breast Cancer Classification of Deep Ultraviolet Fluorescence Images toward Intra-Operative Margin Assessment.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Breast conserving surgery aims at the complete removal of malignant lesions while minimizing healthy tissue loss. To ensure the balance between complete resection of the cancer and conservation of healthy tissue, intra-operative margin assessment is ...

DeepLearnMOR: a deep-learning framework for fluorescence image-based classification of organelle morphology.

Plant physiology
The proper biogenesis, morphogenesis, and dynamics of subcellular organelles are essential to their metabolic functions. Conventional techniques for identifying, classifying, and quantifying abnormalities in organelle morphology are largely manual an...

ChemFLuo: a web-server for structure analysis and identification of fluorescent compounds.

Briefings in bioinformatics
BACKGROUND: Fluorescent detection methods are indispensable tools for chemical biology. However, the frequent appearance of potential fluorescent compound has greatly interfered with the recognition of compounds with genuine activity. Such fluorescen...

A new method using machine learning for automated image analysis applied to chip-based digital assays.

The Analyst
Chip-based digital assays such as the digital polymerase chain reaction (digital PCR), digital loop-mediated amplification (digital LAMP), digital enzyme-linked immunosorbent assay (digital ELISA) and digital proximity ligation assay (digital PLA) ne...

Smart Data Analytics approach to model Complex Biochemical Oscillations in Hippocampal Neurons.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Calcium spiking can be used for drug screening studies in pharmaceutical industries. However, performing experiments for multiple drugs and doses are highly expensive. The oscillatory behavior of calcium spiking data demonstrates extreme nonlinearity...

[Rapid Identification of Epicarpium Citri Grandis via Infrared Spectroscopy and Fluorescence Spectrum Imaging Technology Combined with Neural Network].

Guang pu xue yu guang pu fen xi = Guang pu
To explore rapid reliable methods for detection of Epicarpium citri grandis (ECG), the experiment using Fourier Transform Attenuated Total Reflection Infrared Spectroscopy (FTIR/ATR) and Fluorescence Spectrum Imaging Technology combined with Multilay...