AIMC Topic: Fungal Proteins
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Rapid Rule Out of Culture-Negative Bloodstream Infections by Use of a Novel Approach to Universal Detection of Bacteria and Fungi.
The journal of applied laboratory medicine
Nov 20, 2018
BACKGROUND: Currently it can take up to 5 days to rule out bloodstream infection. With the low yield of blood cultures (approximately 10%), a significant number of patients are potentially exposed to inappropriate therapy that can lead to adverse eve...
Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0.
Molecular plant pathology
May 11, 2018
Plant-pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive improvements to EffectorP, the first machine learning classifier for fungal effector prediction. EffectorP 2.0 is now trained on a larger set of effectors...
ApoplastP: prediction of effectors and plant proteins in the apoplast using machine learning.
The New phytologist
Dec 15, 2017
The plant apoplast is integral to intercellular signalling, transport and plant-pathogen interactions. Plant pathogens deliver effectors both into the apoplast and inside host cells, but no computational method currently exists to discriminate betwee...
A deep auto-encoder model for gene expression prediction.
BMC genomics
Nov 17, 2017
BACKGROUND: Gene expression is a key intermediate level that genotypes lead to a particular trait. Gene expression is affected by various factors including genotypes of genetic variants. With an aim of delineating the genetic impact on gene expressio...
A novel aspartic protease from Rhizomucor miehei expressed in Pichia pastoris and its application on meat tenderization and preparation of turtle peptides.
Food chemistry
Oct 23, 2017
A novel aspartic protease gene (RmproA) was cloned from the thermophilic fungus Rhizomucor miehei CAU432 and expressed in Pichia pastoris. The RmproA was successfully expressed in P. pastoris as an active extracellular protease. High protease activit...
Investigating the antifungal activity and mechanism of a microbial pesticide Shenqinmycin against Phoma sp.
Pesticide biochemistry and physiology
Aug 30, 2017
Tea white scab (TWS) is a major disease affecting tea trees in mid-elevation regions and often occurs during rainy seasons with low temperatures. This disease is caused by the fungal pathogen Phoma sp. TWS can infect young stems, tender leaves, and t...
Phenazines
Plant Structures
Mycelium
Ascomycota
Gene Expression Regulation, Fungal
Genes, Fungal
Down-Regulation
Up-Regulation
Homeostasis
RNA, Messenger
Culture Media
Chromatography, Liquid
Camellia sinensis
Microbial Sensitivity Tests
Nanotechnology
Plant Diseases
Energy Metabolism
Oxidation-Reduction
Fungal Proteins
Antifungal Agents
Tandem Mass Spectrometry
Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning.
G3 (Bethesda, Md.)
May 5, 2017
High-throughput microscopy of many single cells generates high-dimensional data that are far from straightforward to analyze. One important problem is automatically detecting the cellular compartment where a fluorescently-tagged protein resides, a ta...
An improved method for functional similarity analysis of genes based on Gene Ontology.
BMC systems biology
Dec 23, 2016
BACKGROUND: Measures of gene functional similarity are essential tools for gene clustering, gene function prediction, evaluation of protein-protein interaction, disease gene prioritization and other applications. In recent years, many gene functional...
Machine Learning of Protein Interactions in Fungal Secretory Pathways.
PloS one
Jul 21, 2016
In this paper we apply machine learning methods for predicting protein interactions in fungal secretion pathways. We assume an inter-species transfer setting, where training data is obtained from a single species and the objective is to predict prote...
Detection of overlapping protein complexes in gene expression, phenotype and pathways of Saccharomyces cerevisiae using Prorank based Fuzzy algorithm.
Gene
Jan 22, 2016
Proteins show their functional activity by interacting with other proteins and forms protein complexes since it is playing an important role in cellular organization and function. To understand the higher order protein organization, overlapping is an...
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