AIMC Topic: Gallium Radioisotopes

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Prostate Cancer Nodal Staging: Using Deep Learning to Predict Ga-PSMA-Positivity from CT Imaging Alone.

Scientific reports
Lymphatic spread determines treatment decisions in prostate cancer (PCa) patients. 68Ga-PSMA-PET/CT can be performed, although cost remains high and availability is limited. Therefore, computed tomography (CT) continues to be the most used modality f...

Machine learning for differentiating metastatic and completely responded sclerotic bone lesion in prostate cancer: a retrospective radiomics study.

The British journal of radiology
OBJECTIVE: Using CT texture analysis and machine learning methods, this study aims to distinguish the lesions imaged via 68Ga-prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/CT as metastatic and completely responded in pa...

Automated Whole-Body Bone Lesion Detection for Multiple Myeloma on Ga-Pentixafor PET/CT Imaging Using Deep Learning Methods.

Contrast media & molecular imaging
The identification of bone lesions is crucial in the diagnostic assessment of multiple myeloma (MM). Ga-Pentixafor PET/CT can capture the abnormal molecular expression of CXCR-4 in addition to anatomical changes. However, whole-body detection of doze...

Ga PSMA-11 PET with CT urography protocol in the initial staging and biochemical relapse of prostate cancer.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Ga-labelled prostate specific membrane antigen (PSMA) ligand PET/CT is a promising modality in primary staging (PS) and biochemical relapse (BCR) of prostate cancer (PC). However, pelvic nodes or local recurrences can be difficult to diff...

Integration of CT urography improves diagnostic confidence of Ga-PSMA-11 PET/CT in prostate cancer patients.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: To prove the feasibility of integrating CT urography (CTU) into Ga-PSMA-11 PET/CT and to analyze the impact of CTU on assigning focal tracer accumulation in the ureteric space to either ureteric excretion or metastatic disease concerning ...

Focal MRI-Guided Salvage High-Dose-Rate Brachytherapy in Patients With Radiorecurrent Prostate Cancer.

Technology in cancer research & treatment
INTRODUCTION: Whole-gland salvage treatment of radiorecurrent prostate cancer has a high rate of severe toxicity. The standard of care in case of a biochemical recurrence is androgen deprivation treatment, which is associated with morbidity and negat...