AIMC Topic: Gastrointestinal Microbiome
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Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson's disease.
Nature communications
May 7, 2025
There is strong interest in using the gut microbiome for Parkinson's disease (PD) diagnosis and treatment. However, a consensus on PD-associated microbiome features and a multi-study assessment of their diagnostic value is lacking. Here, we present a...
Learning a deep language model for microbiomes: The power of large scale unlabeled microbiome data.
PLoS computational biology
May 7, 2025
We use open source human gut microbiome data to learn a microbial "language" model by adapting techniques from Natural Language Processing (NLP). Our microbial "language" model is trained in a self-supervised fashion (i.e., without additional externa...
Unraveling MASLD: The Role of Gut Microbiota, Dietary Modulation, and AI-Driven Lifestyle Interventions.
Nutrients
May 4, 2025
Gut microbiota has a crucial role in the pathophysiology of metabolic-associated steatotic liver disease (MASLD), influencing various metabolic mechanisms and contributing to the development of the disease. Dietary interventions targeting gut microbi...
Interpretable machine learning algorithms reveal gut microbiome features associated with atopic dermatitis.
Frontiers in immunology
May 1, 2025
BACKGROUND: The "gut-skin axis" has been proposed to play an important role in the development and symptoms of atopic dermatitis. Therefore, we have constructed an interpretable machine learning framework to quantitatively screen key gut flora.
Gut microbiota-derived extracellular vesicles form a distinct entity from gut microbiota.
mSystems
Apr 29, 2025
Extracellular vesicles (EVs), nanoparticles secreted by both gram-negative and gram-positive bacteria, carry various biomolecules and cross biological barriers. Gut microbiota-derived EVs are currently being investigated as a communication mechanism ...
Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study.
mSystems
Apr 29, 2025
Colorectal cancer (CRC) is the third most common cancer, and it can be prevented by performing early screening. As a hallmark of cancer, the human microbiome plays important roles in the occurrence and development of CRC. Recently, the blood microbio...
Biological age prediction in schizophrenia using brain MRI, gut microbiome and blood data.
Brain research bulletin
Apr 27, 2025
The study of biological age prediction using various biological data has been widely explored. However, single biological data may offer limited insights into the pathological process of aging and diseases. Here we evaluated the performance of machin...
Hybrid Neural network and machine learning models with improved optimization method for gut microbiome effects on the sleep quality in patients with endometriosis.
Computer methods and programs in biomedicine
Apr 26, 2025
BACKGROUND AND OBJECTIVE: Endometriosis is a chronic gynecological condition known to affect the quality of life of millions of women globally, often manifesting with symptoms that impact sleep quality. Emerging evidence suggests a crucial role of th...
Pato: prediction of probiotic bacteria using metabolic features.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
Apr 23, 2025
Probiotics have gained recognition for their health-promoting benefits, particularly in the gastrointestinal and immunological systems. Among promising probiotic candidates, Lactobacillus strains, belonging to the lactic acid bacteria (LAB) group, pl...
Recent advances in therapeutic probiotics: insights from human trials.
Clinical microbiology reviews
Apr 22, 2025
SUMMARYRecent advances in therapeutic probiotics have shown promising results across various health conditions, reflecting a growing understanding of the human microbiome's role in health and disease. However, comprehensive reviews integrating the di...
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