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Self-enhanced PEI-Ru(II) complex with polyamino acid as booster to construct ultrasensitive electrochemiluminescence immunosensor for carcinoembryonic antigen detection.

Analytica chimica acta
In this work, the luminophor tris (4,4'-dicarboxylicacid-2,2'-bipyridyl) ruthenium (II) dichloride (Ru(dcbpy)) was linked to coreactant polyethylenimine (PEI) with effectively shorted distance, forming a novel self-enhanced PEI-Ru(II) complex to fabr...

Dual-responsive electrochemical immunosensor for detection of insulin based on dual-functional zinc silicate spheres-palladium nanoparticles.

Talanta
In this study, described an electrochemical immunoassay for insulin that is based on the use of zinc silicate spheres loaded with palladium nanoparticles (ZnSiO-PdNPs) that act as dual-function labels. The ZnSiO-PdNPs display high electrocatalytic ac...

A novel sandwich-type electrochemical immunosensor for PSA detection based on PtCu bimetallic hybrid (2D/2D) rGO/g-CN.

Biosensors & bioelectronics
In this work, a sensitive sandwich-type electrochemical immunosensor was designed for the quantitative detection of prostate-specific antigen (PSA) by amperometric i-t. The Au loaded on thionine functionalized graphene oxide (Au@Th/GO) was used as a ...

A novel aptasensor for the colorimetric detection of S. typhimurium based on gold nanoparticles.

International journal of food microbiology
A simple, fast and convenient colorimetric aptasensor was fabricated for the detection of Salmonella typhimurium (S. typhimurium) which was based on the color change effect of gold nanoparticles (GNPs). S. typhimurium is one of the most common causes...

Highly sensitive detection of multiple tumor markers for lung cancer using gold nanoparticle probes and microarrays.

Analytica chimica acta
Assay of multiple serum tumor markers such as carcinoembryonic antigen (CEA), cytokeratin 19 fragment antigen (CYFRA21-1), and neuron specific enolase (NSE), is important for the early diagnosis of lung cancer. Dickkopf-1 (DKK1), a novel serological ...

Anticancer activity of biologically synthesized silver and gold nanoparticles on mouse myoblast cancer cells and their toxicity against embryonic zebrafish.

Materials science & engineering. C, Materials for biological applications
The aim of this study was to evaluate the anticancer activity of bioinspired silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) against mouse myoblast cancer cells (CC). Both AgNPs and AuNPs were biologically synthesized using Spinacia olera...

Metal-Organic Framework Nanomaterials as Novel Signal Probes for Electron Transfer Mediated Ultrasensitive Electrochemical Immunoassay.

Analytical chemistry
A novel and simple electrochemical immunoassay for C-reactive protein was developed using metal-organic frameworks (Au-MOFs) as signal unit. In this study, we found MOFs could be used as signal probe. And this new class of signal probe differs from t...

Surface enhanced Raman spectroscopy (SERS) as a method for the toxicological analysis of synthetic cannabinoids.

Talanta
Synthetic cannabinoids (K2, spice) present problems in forensic investigations because standard presumptive methods, such as immunoassays, are insufficiently specific for the wide range of potential target compounds. This issue can lead to problems w...