AIMC Topic: Healthy Volunteers

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Calculation of upper esophageal sphincter restitution time from high resolution manometry data using machine learning.

Physiology & behavior Aug 10, 2016
OBJECTIVE: After swallowing, the upper esophageal sphincter (UES) needs a certain amount of time to return from maximum pressure to the resting condition. Disturbances of sphincter function not only during the swallowing process but also in this phas...
Humans Machine Learning Retrospective Studies Female Healthy Volunteers Pressure Deglutition Manometry Esophageal Sphincter, Upper Young Adult Adult Male Middle Aged Time Factors
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Daily changes of individual gait patterns identified by means of support vector machines.

Gait & posture Jul 29, 2016
Despite the common knowledge about the individual character of human gait patterns and about their non-repeatability, little is known about their stability, their interactions and their changes over time. Variations of gait patterns are typically des...
Humans Female Models, Biological Adult Circadian Rhythm Biomechanical Phenomena Healthy Volunteers Male Movement Support Vector Machine Gait
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The effect of geographical indices on left ventricular structure in healthy Han Chinese population.

International journal of biometeorology Jul 28, 2016
The left ventricular posterior wall thickness (LVPWT) and interventricular septum thickness (IVST) are generally regarded as the functional parts of the left ventricular (LV) structure. This paper aims to examine the effects of geographical indices o...
Climate Heart Ventricles Neural Networks, Computer Asian People Female Weather Aged Reference Values Aged, 80 and over Healthy Volunteers Humans Young Adult Adult Male Middle Aged China Adolescent
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Classification of Motor Imagery EEG Signals with Support Vector Machines and Particle Swarm Optimization.

Computational and mathematical methods in medicine May 30, 2016
Support vector machines are powerful tools used to solve the small sample and nonlinear classification problems, but their ultimate classification performance depends heavily upon the selection of appropriate kernel and penalty parameters. In this st...
Models, Statistical Principal Component Analysis Electroencephalography Signal Processing, Computer-Assisted Hand Healthy Volunteers Foot Motor Skills Movement Imagination Computer Simulation Reproducibility of Results Adult Signal Transduction Support Vector Machine Humans Algorithms
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Classifying work rate from heart rate measurements using an adaptive neuro-fuzzy inference system.

Applied ergonomics Jan 2, 2016
In a new approach based on adaptive neuro-fuzzy inference systems (ANFIS), field heart rate (HR) measurements were used to classify work rate into four categories: very light, light, moderate, and heavy. Inter-participant variability (physiological a...
Male Middle Aged Fuzzy Logic Oxygen Consumption Physical Exertion Humans Neural Networks, Computer Young Adult Adult Sensitivity and Specificity Work Task Performance and Analysis Motor Activity Body Weight Heart Rate Healthy Volunteers Energy Metabolism Observer Variation
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Muscle damage and immune responses to prolonged exercise in environmental extreme conditions.

The Journal of sports medicine and physical fitness Sep 1, 2015
BACKGROUND: This study aimed to investigate the effect of prolonged exercise with and without a thermal clamp on leukocyte cell, stress hormones, cytokine and muscle damage responses.
Leukocyte Count Humans Physical Endurance Muscle Fatigue Adult Stress, Physiological Cytokines Male Random Allocation Biomarkers Exercise Hot Temperature Young Adult Exercise Test Humidity Healthy Volunteers
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A Sensitive and Specific Neural Signature for Picture-Induced Negative Affect.

PLoS biology Jun 22, 2015
Neuroimaging has identified many correlates of emotion but has not yet yielded brain representations predictive of the intensity of emotional experiences in individuals. We used machine learning to identify a sensitive and specific signature of emoti...
Brain Female Young Adult Humans Affect Adult Sensitivity and Specificity Machine Learning Male Pain Perception Middle Aged Adolescent Magnetic Resonance Imaging Healthy Volunteers
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Population pharmacokinetic/pharmacodynamic assessment of pharmacological effect of a selective estrogen receptor β agonist on total testosterone in healthy men.

Clinical pharmacology in drug development Jun 8, 2015
BACKGROUND: LY500307 is a highly selective estrogen receptor β (ERβ) agonist, which loses its selectivity at high dose and leads to undesirable suppression of total testosterone (TT) concentration. The objective of the present analysis was to define ...
Fourier Analysis London Selective Estrogen Receptor Modulators Nonlinear Dynamics Benzopyrans Humans Drug Administration Schedule Models, Biological Biomarkers Circadian Rhythm Estrogen Receptor beta Administration, Oral Young Adult Adult Cross-Over Studies Male Healthy Volunteers Middle Aged Testosterone Single-Blind Method
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Recognition of activities of daily living in healthy subjects using two ad-hoc classifiers.

Biomedical engineering online Jun 6, 2015
BACKGROUND: Activities of daily living (ADL) are important for quality of life. They are indicators of cognitive health status and their assessment is a measure of independence in everyday living. ADL are difficult to reliably assess using questionna...
Bayes Theorem Wireless Technology Circadian Rhythm Thermometry Supervised Machine Learning Aged Activities of Daily Living Humans Adult Healthy Volunteers Algorithms Sleep Male Female Middle Aged Infrared Rays Decision Trees Accelerometry Medical Records Neuropsychological Tests
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Hemoglobin-based oxygen carriers promote systemic hyperfibrinolysis that is both dependent and independent of plasmin.

The Journal of surgical research Apr 25, 2015
BACKGROUND: Hyperfibrinolysis plays an integral role in the genesis of trauma-induced coagulopathy. Recent data demonstrate that red blood cell lysis promotes fibrinolysis; however, the mechanism is unclear. Hemoglobin-based oxygen carriers (HBOCs) h...
Thrombelastography Fibrinolysis Humans Hemoglobins Biomarkers Healthy Volunteers Adult Blood Substitutes Male Fibrinolysin
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