AIMC Topic: Hematopoietic Stem Cell Transplantation

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A Systematic Review of Machine Learning Techniques in Hematopoietic Stem Cell Transplantation (HSCT).

Sensors (Basel, Switzerland)
Machine learning techniques are widely used nowadays in the healthcare domain for the diagnosis, prognosis, and treatment of diseases. These techniques have applications in the field of hematopoietic cell transplantation (HCT), which is a potentially...

Machine learning predicts stem cell transplant response in severe scleroderma.

Annals of the rheumatic diseases
OBJECTIVE: The Scleroderma: Cyclophosphamide or Transplantation (SCOT) trial demonstrated clinical benefit of haematopoietic stem cell transplant (HSCT) compared with cyclophosphamide (CYC). We mapped PBC (peripheral blood cell) samples from the SCOT...

Machine Learning Classification Algorithms to Predict aGvHD following Allo-HSCT: A Systematic Review.

Methods of information in medicine
BACKGROUND:  The acute graft-versus-host disease (aGvHD) is the most important cause of mortality in patients receiving allogeneic hematopoietic stem cell transplantation. Given that it occurs at the stage of severe tissue damage, its diagnosis is la...

Machine learning reveals chronic graft--host disease phenotypes and stratifies survival after stem cell transplant for hematologic malignancies.

Haematologica
The application of machine learning in medicine has been productive in multiple fields, but has not previously been applied to analyze the complexity of organ involvement by chronic graft--host disease. Chronic graft--host disease is classified by an...

Artificial Intelligence Approaches in Hematopoietic Cell Transplantation: A Review of the Current Status and Future Directions.

Turkish journal of haematology : official journal of Turkish Society of Haematology
The evidence-based literature on healthcare is currently expanding exponentially. The opportunities provided by the advancement in artificial intelligence (AI) tools such as machine learning are appealing in tackling many of the current healthcare ch...

A cure-rate model for Q-learning: Estimating an adaptive immunosuppressant treatment strategy for allogeneic hematopoietic cell transplant patients.

Biometrical journal. Biometrische Zeitschrift
Cancers treated by transplantation are often curative, but immunosuppressive drugs are required to prevent and (if needed) to treat graft-versus-host disease. Estimation of an optimal adaptive treatment strategy when treatment at either one of two st...

Evaluation of a Machine Learning-Based Prognostic Model for Unrelated Hematopoietic Cell Transplantation Donor Selection.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
The survival of patients undergoing hematopoietic cell transplantation (HCT) from unrelated donors for acute leukemia exhibits considerable variation, even after stringent genetic matching. To improve the donor selection process, we attempted to crea...