Hepatitis B is a global health burden and can persist for years, with nearly two billion infections worldwide, where its spread is influenced by environmental heterogeneity, host-pathogen interactions, and vaccination-induced immune variability. Prop...
Hepatitis B virus-related acute-on-chronic liver failure (ACHBLF) is a severe condition associated with short-term mortality without liver transplantation. Substantial evidence indicates that necroptosis and immune infiltration play critical roles in...
Endoplasmic reticulum stress (ERS) has been implicated in a range of biological processes, yet its specific involvement in Hepatitis B virus-associated acute liver failure (HBV-ALF) remains poorly understood. This study aimed to identify key ERS-rela...
BACKGROUND: Individualized risk stratification in hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) remains challenging. This study aimed to develop and validate a multi-task deep learning model using longitudinal liver ultrasound i...
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
Aug 9, 2025
PURPOSE: Among patients with hepatitis B virus-associated liver cirrhosis (HBV-LC), there may be differences in the hepatic parenchyma between those with and without hepatocellular carcinoma (HCC). Proton MR spectroscopy (H-MRS) is a well-established...
Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC), yet the mechanisms by which HBV triggers HCC and how it interacts with the immune system remain largely undefined. In this study, 53 immune-related key genes invol...
Viral infections have spread globally, profoundly affecting social and economic aspects of life and causing widespread suffering. Infection caused by the hepatitis B virus (HBV) is one of the significant global health challenges but can be effectivel...
OBJECTIVE: To develop and validate a novel diagnostic model for detecting bacterial infections in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) using advanced machine learning algorithms. The focus is on improving ...
Medical interns are at high risk of acquiring Hepatitis B Virus (HBV) infection during their training. HBV vaccination is the most effective measure to reduce the global incidence of HBV. The duration of protection after HBV vaccination is still cont...
BACKGROUND: Immune checkpoint inhibitors have proven efficacy against hepatitis B-virus positive hepatocellular. However, Immunotherapy-related adverse reactions are still a major challenge faced by tumor immunotherapy, so it is urgent to establish n...
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