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Hippocampus

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A semi-supervised deep neuro-fuzzy iterative learning system for automatic segmentation of hippocampus brain MRI.

Mathematical biosciences and engineering : MBE
The hippocampus is a small, yet intricate seahorse-shaped tiny structure located deep within the brain's medial temporal lobe. It is a crucial component of the limbic system, which is responsible for regulating emotions, memory, and spatial navigatio...

Enhanced detection of mild cognitive impairment in Alzheimer's disease: a hybrid model integrating dual biomarkers and advanced machine learning.

BMC geriatrics
Alzheimer's disease (AD) is a complex, progressive, and irreversible neurodegenerative disorder marked by cognitive decline and memory loss. Early diagnosis is the most effective strategy to slow the disease's progression. Mild Cognitive Impairment (...

Self-supervised learning of scale-invariant neural representations of space and time.

Journal of computational neuroscience
Hippocampal representations of space and time seem to share a common coding scheme characterized by neurons with bell-shaped tuning curves called place and time cells. The properties of the tuning curves are consistent with Weber's law, such that, in...

Brain mapping, biomarker identification and using machine learning method for diagnosis of anxiety during emotional face in preschool children.

Brain research bulletin
BACKGROUND: Due to the importance and the consequences of anxiety, the goals of the current study are brain mapping, biomarker identification and the use of an assessment method for diagnosis of anxiety during emotional face in preschool children.

From Genes to Metabolites: HSP90B1's Role in Alzheimer's Disease and Potential for Therapeutic Intervention.

Neuromolecular medicine
Alzheimer's disease (AD) is a prototypical neurodegenerative disorder, predominantly affecting individuals in the presenile and elderly populations, with an etiology that remains elusive. This investigation aimed to elucidate the alterations in anoik...

Convolutional Neural Networks for the segmentation of hippocampal structures in postmortem MRI scans.

Journal of neuroscience methods
BACKGROUND: The hippocampus plays a crucial role in memory and is one of the first structures affected by Alzheimer's disease. Postmortem MRI offers a way to quantify the alterations by measuring the atrophy of the inner structures of the hippocampus...

Memristor-based circuit design of interweaving mechanism of emotional memory in a hippocamp-brain emotion learning model.

Neural networks : the official journal of the International Neural Network Society
Endowing robots with human-like emotional and cognitive abilities has garnered widespread attention, driving deep investigations into the complexities of these processes. However, few studies have examined the intricate circuits that govern the inter...

Comparison of surgical approaches to the hippocampal formation with artificial intelligence.

Neurosurgical review
The relatively complex functional anatomy of the mediobasal temporal region makes surgical approaches to this area challenging. Several studies describe various surgical approaches, along with their combinations and modifications, to reach lesions of...

Hybrid neural networks for continual learning inspired by corticohippocampal circuits.

Nature communications
Current artificial systems suffer from catastrophic forgetting during continual learning, a limitation absent in biological systems. Biological mechanisms leverage the dual representation of specific and generalized memories within corticohippocampal...

Replay as a Basis for Backpropagation Through Time in the Brain.

Neural computation
How episodic memories are formed in the brain is a continuing puzzle for the neuroscience community. The brain areas that are critical for episodic learning (e.g., the hippocampus) are characterized by recurrent connectivity and generate frequent off...