AIMC Topic: Humans

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Machine Learning-Driven Identification of Molecular Subgroups in Medulloblastoma via Gene Expression Profiling.

Clinical oncology (Royal College of Radiologists (Great Britain))
AIMS: Medulloblastoma (MB) is the most prevalent malignant brain tumour in children, characterised by substantial molecular heterogeneity across its subgroups. Accurate classification is pivotal for personalised treatment strategies and prognostic as...

Molecular structure of NRG-1 protein and its impact on adult hypertension and heart failure: A new clinical Indicator diagnosis based on advanced machine learning.

International journal of biological macromolecules
The purpose of this study was to investigate the molecular structure of NRG-1 protein and its mechanism of action in adult hypertensive heart failure. The amino acid sequence of NRG-1 protein was analyzed by bioinformatics method. High-throughput seq...

Performance evaluation of ChatGPT-4.0 and Gemini on image-based neurosurgery board practice questions: A comparative analysis.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
INTRODUCTION: Artificial intelligence (AI) has gained significant attention in medicine, particularly in neurosurgery, where its potential is often discussed and occasionally feared. Large language models (LLMs), such as ChatGPT-4.0 (OpenAI) and Gemi...

Chat GPT vs. Clinical Decision Support Systems in the Analysis of Drug-Drug Interactions.

Clinical pharmacology and therapeutics
The current standard method for the analysis of potential drug-drug interactions (pDDIs) is time-consuming and includes the use of multiple clinical decision support systems (CDSSs) and the interpretation by healthcare professionals. With the emergen...

Staying for food by urban birds: Insights from neural network analysis into adaptive strategies.

Environmental management
Previous work showed that animals have demonstrated remarkable adaptability by actively integrating into urban environments. However, there is no essential difference between urban and rural areas but food availability. The behavioral mechanisms and ...

Artificial intelligence in digital pathology - time for a reality check.

Nature reviews. Clinical oncology
The past decade has seen the introduction of artificial intelligence (AI)-based approaches aimed at optimizing several workflows across many medical specialties. In clinical oncology, the most promising applications include those involving image anal...

[Transformation of free-text radiology reports into structured data].

Radiologie (Heidelberg, Germany)
BACKGROUND: The rapid development of large language models (LLMs) opens up new possibilities for the automated processing of medical texts. Transforming unstructured radiology reports into structured data is crucial for efficient use in clinical deci...

DeepInterAware: Deep Interaction Interface-Aware Network for Improving Antigen-Antibody Interaction Prediction from Sequence Data.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Identifying interactions between candidate antibodies and target antigens is a key step in developing effective human therapeutics. The antigen-antibody interaction (AAI) occurs at the structural level, but the limited structure data poses a signific...

Screening of estrogen receptor activity of per- and polyfluoroalkyl substances based on deep learning and in vivo assessment.

Environmental pollution (Barking, Essex : 1987)
Over the past decades, exposure to per- and polyfluoroalkyl substances (PFAS), a group of synthetic chemicals notorious for their environmental persistence, has been shown to pose increased health risks. Despite that some PFAS were reported to have e...

Artificial intelligence-assisted point-of-care devices for lung cancer.

Clinica chimica acta; international journal of clinical chemistry
Lung cancer is the leading cause of cancer-related deaths worldwide, primarily due to late-stage detection, which limits treatment options. Early detection and screening can increase survival rates, but traditional medical imaging methods are costly ...