AIMC Topic: Humans

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A benchmark of deep learning approaches to predict lung cancer risk using national lung screening trial cohort.

Scientific reports
Deep learning (DL) methods have demonstrated remarkable effectiveness in assisting with lung cancer risk prediction tasks using computed tomography (CT) scans. However, the lack of comprehensive comparison and validation of state-of-the-art (SOTA) mo...

Application of machine learning in depression risk prediction for connective tissue diseases.

Scientific reports
This study retrospectively collected clinical data from 480 patients with connective tissue diseases (CTDs) at Nanjing First Hospital between August 2019 and December 2023 to develop and validate a multi-classification machine learning (ML) model for...

Intelligent skin disease prediction system using transfer learning and explainable artificial intelligence.

Scientific reports
Skin diseases impact millions of people around the world and pose a severe risk to public health. These diseases have a wide range of effects on the skin's structure, functionality, and appearance. Identifying and predicting skin diseases are laborio...

A python approach for prediction of physicochemical properties of anti-arrhythmia drugs using topological descriptors.

Scientific reports
In recent years, machine learning has gained substantial attention for its ability to predict complex chemical and biological properties, including those of pharmaceutical compounds. This study proposes a machine learning-based quantitative structure...

Leveraging explainable AI and large-scale datasets for comprehensive classification of renal histologic types.

Scientific reports
Recently, as the number of cancer patients has increased, much research is being conducted for efficient treatment, including the use of artificial intelligence in genitourinary pathology. Recent research has focused largely on the classification of ...

Homo Sapiens Chromosomal Location Ontology: A Framework for Genomic Data in Biomedical Knowledge Graphs.

Scientific data
The Homo sapiens Chromosomal Location Ontology (HSCLO) is designed to facilitate the integration of human genomic features into biomedical knowledge graphs from releases GRCh37 and GRCh38 at multiple resolutions. HSCLO comprises two distinct versions...

Application of functional near-infrared spectroscopy and machine learning to predict treatment response after six months in major depressive disorder.

Translational psychiatry
Depression treatment responses vary widely among individuals. Identifying objective biomarkers with predictive accuracy for therapeutic outcomes can enhance treatment efficiency and avoid ineffective therapies. This study investigates whether functio...

Not seeing the trees for the forest. The impact of neighbours on graph-based configurations in histopathology.

BMC bioinformatics
BACKGROUND: Deep learning (DL) has set new standards in cancer diagnosis, significantly enhancing the accuracy of automated classification of whole slide images (WSIs) derived from biopsied tissue samples. To enable DL models to process these large i...

Assessing chemical exposure risk in breastfeeding infants: An explainable machine learning model for human milk transfer prediction.

Ecotoxicology and environmental safety
Breast milk is essential for infant health, but the transfer of xenobiotic chemicals poses significant risks. Ethical challenges in clinical trials necessitate the use of in vitro predictive models to assess chemical exposure risks in breastfeeding i...

'Applications of machine learning in liposomal formulation and development'.

Pharmaceutical development and technology
Machine learning (ML) has emerged as a transformative tool in drug delivery, particularly in the design and optimization of liposomal formulations. This review focuses on the intersection of ML and liposomal technology, highlighting how advanced algo...