AIMC Topic: Humans

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A robust transfer learning approach for high-dimensional linear regression to support integration of multi-source gene expression data.

PLoS computational biology
Transfer learning aims to integrate useful information from multi-source datasets to improve the learning performance of target data. This can be effectively applied in genomics when we learn the gene associations in a target tissue, and data from ot...

The role of chromatin state in intron retention: A case study in leveraging large scale deep learning models.

PLoS computational biology
Complex deep learning models trained on very large datasets have become key enabling tools for current research in natural language processing and computer vision. By providing pre-trained models that can be fine-tuned for specific applications, they...

Enhancing semantical text understanding with fine-tuned large language models: A case study on Quora Question Pair duplicate identification.

PloS one
Semantical text understanding holds significant importance in natural language processing (NLP). Numerous datasets, such as Quora Question Pairs (QQP), have been devised for this purpose. In our previous study, we developed a Siamese Convolutional Ne...

The advantages of lexicon-based sentiment analysis in an age of machine learning.

PloS one
Assessing whether texts are positive or negative-sentiment analysis-has wide-ranging applications across many disciplines. Automated approaches make it possible to code near unlimited quantities of texts rapidly, replicably, and with high accuracy. C...

Cardiac MR image reconstruction using cascaded hybrid dual domain deep learning framework.

PloS one
Recovering diagnostic-quality cardiac MR images from highly under-sampled data is a current research focus, particularly in addressing cardiac and respiratory motion. Techniques such as Compressed Sensing (CS) and Parallel Imaging (pMRI) have been pr...

A hybrid unsupervised machine learning model with spectral clustering and semi-supervised support vector machine for credit risk assessment.

PloS one
In credit risk assessment, unsupervised classification techniques can be introduced to reduce human resource expenses and expedite decision-making. Despite the efficacy of unsupervised learning methods in handling unlabeled datasets, their performanc...

Glycosylation profiling of triple-negative breast cancer: clinical and immune correlations and identification of LMAN1L as a biomarker and therapeutic target.

Frontiers in immunology
INTRODUCTION: Breast cancer (BC) is the most prevalent malignant tumor in women, with triple-negative breast cancer (TNBC) showing the poorest prognosis among all subtypes. Glycosylation is increasingly recognized as a critical biomarker in the tumor...

Developing and validating a machine learning model to predict multidrug-resistant -related septic shock.

Frontiers in immunology
BACKGROUND: Multidrug-resistant Klebsiella pneumoniae (MDR-KP) infections pose a significant global healthcare challenge, particularly due to the high mortality risk associated with septic shock. This study aimed to develop and validate a machine lea...

Identification of hub genes and immune-related pathways in acute myeloid leukemia: insights from bioinformatics and experimental validation.

Frontiers in immunology
BACKGROUND: This study aims to identify the hub genes and immune-related pathways in acute myeloid leukemia (AML) to provide new theories for immunotherapy.

The influence of factors related to public health campaigns on vaccination behavior among population of Wuxi region, China.

Frontiers in public health
BACKGROUND: Public health campaigns are essential for promoting vaccination behavior, but factors such as socioeconomic status, geographical location, campaign quality, and service accessibility influence vaccine uptake. In the Wuxi region of China, ...