AIMC Topic: Humans

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A computational study of cardiac glycosides from Vernonia amygdalina as PI3K inhibitors for targeting HER2 positive breast cancer.

Journal of computer-aided molecular design Jul 6, 2025
The PI3K/Akt pathway plays a crucial role in regulating a broad network of proteins involved in the proliferation of HER2-positive breast cancer. The ethyl acetate fraction of Vernonia amygdalina, which contains cardiac glycosides, has been shown to ...
Protein Kinase Inhibitors Phosphoinositide-3 Kinase Inhibitors Cardiac Glycosides Molecular Dynamics Simulation Receptor, ErbB-2 Humans Molecular Docking Simulation Quantitative Structure-Activity Relationship Class I Phosphatidylinositol 3-Kinases Machine Learning Phosphatidylinositol 3-Kinases Female Breast Neoplasms
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The application of improved AFCNN model for children's psychological emotion recognition.

Scientific reports Jul 6, 2025
Children's mental health has become an increasingly prominent concern in modern education. However, insufficient attention from schools and families to children's psychological and emotional issues has exacerbated the problem. This study proposes a p...
Humans Neural Networks, Computer Female Male Child Emotions Attention
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Comparing traditional natural language processing and large language models for mental health status classification: a multi-model evaluation.

Scientific reports Jul 6, 2025
The substantial increase in mental health disorders globally necessitates scalable, accurate tools for detecting and classifying these conditions in digital environments. This study addresses the critical challenge of automated mental health classifi...
Large Language Models Humans Mental Disorders Mental Health Social Media Natural Language Processing
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Interpretable machine learning models for survival prediction in prostate cancer bone metastases.

Scientific reports Jul 6, 2025
Prostate cancer bone metastasis (PCBM) is a highly lethal condition with limited survival. Accurate survival prediction is essential for managing these typically incurable patients. However, existing clinical models lack precision. This study seeks t...
Kaplan-Meier Estimate Prostatic Neoplasms SEER Program Proportional Hazards Models Middle Aged ROC Curve Bone Neoplasms Humans Machine Learning Prognosis Aged Male
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GPS-based street-view greenspace exposure and wearable assessed physical activity in a prospective cohort of US women.

The international journal of behavioral nutrition and physical activity Jul 6, 2025
BACKGROUND: Increasing evidence positively links greenspace and physical activity (PA). However, most studies use measures of greenspace, such as satellite-based vegetation indices around the residence, which fail to capture ground-level views and da...
United States Residence Characteristics Neighborhood Characteristics Exercise Geographic Information Systems Wearable Electronic Devices Environment Design Walking Humans Prospective Studies Female Adult Middle Aged
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Imaging and pulmonary function techniques in ARDS diagnosis and management: current insights and challenges.

Critical care (London, England) Jul 6, 2025
Acute Respiratory Distress Syndrome (ARDS) is a life-threatening condition characterized by acute onset of respiratory failure, which presents significant challenges in diagnosis and management. Its heterogeneity, with diverse underlying aetiologies ...
Tomography, X-Ray Computed Lung Respiratory Distress Syndrome Humans Disease Management Respiratory Function Tests
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MIDAS: a technology-enabled hub-and-spoke system for the collection and dissemination of high-quality medical datasets in India.

BMC medical informatics and decision making Jul 6, 2025
BACKGROUND: The need for better AI models fuels the demand for larger and larger high-quality datasets with significant diversity. Over the years, many medical imaging datasets have been published globally, but existing datasets do not contain enough...
Diagnostic Imaging Artificial Intelligence Information Dissemination Databases, Factual Humans Datasets as Topic India
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Automated facial nerve identification in microsurgery with an improved unet.

Journal of robotic surgery Jul 6, 2025
To develop a deep-learning model that improves the segmentation and detection of Facial Nerve in microsurgery, thereby increasing surgical precision and safety. We collected videos from 25 patients undergoing facial nerve decompression microsurgery. ...
Robotic Surgical Procedures Humans Facial Nerve Deep Learning Microsurgery
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Machine learning models to predict the zero-fragment rate and lower pole access with FANS during flexible Ureteroscopy-an EAU section of endourology study.

World journal of urology Jul 6, 2025
INTRODUCTION: Suction devices such as flexible and navigable suction ureteral access sheath (FANS) are promising tools to reach the zero-fragment rate (ZFR) after flexible ureteroscopy (FURS) and laser lithotripsy. FANS could especially be useful for...
Machine Learning Prospective Studies Female Humans Kidney Calculi Ureteroscopy Ureteroscopes Adult Male Middle Aged
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Psoas muscle CT radiomics-based machine learning models to predict response to infliximab in patients with Crohn's disease.

Annals of medicine Jul 5, 2025
BACKGROUND: Crohn's disease (CD) is a chronic inflammatory bowel disease, with infliximab (IFX) commonly used for treatment. However, no clinically applicable model currently exists to predict the response of patients with CD to IFX therapy. Given th...
Gastrointestinal Agents Psoas Muscles Retrospective Studies Sarcopenia Middle Aged Infliximab Tomography, X-Ray Computed Humans Adult ROC Curve Female Crohn Disease Radiomics Treatment Outcome Machine Learning Male
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