AIMC Topic: Humans

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Exploring the mechanism of metabolic cell death-related genes AKR1C2 and MAP1LC3A as biomarkers in Parkinson's disease.

Scientific reports
There is a strong relationship between metabolic cell death (MCD) and neurodegenerative diseases. However, the involvement of metabolic cell death (MCD)-related genes (MCDRGs) in Parkinson's disease (PD) pathogenesis remains poorly analyzed. Integrat...

A hybrid framework of generative deep learning for antiviral peptide discovery.

Scientific reports
Antiviral peptides (AVPs) hold great potential for combating viral infections, yet their discovery and development remain challenging. In this study, we present a hybrid model combining Wasserstein Generative Adversarial Networks with Gradient Penalt...

Poincare guided geometric UNet for left atrial epicardial adipose tissue segmentation in Dixon MRI images.

Scientific reports
Epicardial Adipose Tissue (EAT) is a recognized risk factor for cardiovascular diseases and plays a pivotal role in the pathophysiology of Atrial Fibrillation (AF). Accurate automatic segmentation of the EAT around the Left Atrium (LA) from Magnetic ...

Decision level scheme for fusing multiomics and histology slide images using deep neural network for tumor prognosis prediction.

Scientific reports
Molecular biostatistical workflows in oncology often rely on predictive models that use multimodal data. Advances in deep learning and artificial intelligence technologies have enabled the multimodal fusion of large volumes of multimodal data. Here, ...

BaliMask3D dataset for 3D completion and reconstruction of traditional Balinese masks.

Scientific data
The BaliMask3D dataset provides high-quality 3D models of traditional Balinese masks to support 3D completion and reconstruction tasks, addressing the need for cultural heritage preservation. Digitized using 360-degree photogrammetry, the dataset com...

Integrating artificial intelligence in community-based diabetes care programmes: enhancing inclusiveness, diversity, equity and accessibility a realist review protocol.

BMJ open
INTRODUCTION: Marginalised populations-such as racialised groups, low-income individuals, newcomers and those in rural areas-disproportionately experience severe diabetes-related complications, including diabetic foot ulcers, retinopathy and amputati...

Evaluating the Usability of an HIV Prevention Artificial Intelligence Chatbot in Malaysia: National Observational Study.

JMIR human factors
BACKGROUND: Malaysia, an upper middle-income country in the Asia-Pacific region, has an HIV epidemic that has transitioned from needle sharing to sexual transmission, mainly in men who have sex with men (MSM). MSM are the most vulnerable population f...

Exploring the Dilemma of AI Use in Medical Research and Knowledge Synthesis: A Perspective on Deep Research Tools.

Journal of medical Internet research
Advances in artificial intelligence (AI) promise to reshape the landscape of scientific inquiry. Amidst all these, OpenAI's latest tool, Deep Research, stands out for its potential to revolutionize how researchers engage with the literature. However,...

Multimodal Detection of Agitation in People With Dementia in Clinical Settings: Observational Pilot Study.

JMIR aging
BACKGROUND: Dementia is a progressive neurodegenerative condition that affects millions worldwide, often accompanied by agitation and aggression (AA), which contribute to patient distress and increased health care burden. Existing assessment methods ...

Development and Validation of a Large Language Model-Powered Chatbot for Neurosurgery: Mixed Methods Study on Enhancing Perioperative Patient Education.

Journal of medical Internet research
BACKGROUND: Perioperative education is crucial for optimizing outcomes in neuroendovascular procedures, where inadequate understanding can heighten patient anxiety and hinder care plan adherence. Current education models, reliant on traditional consu...