BMC medical informatics and decision making
Dec 30, 2020
BACKGROUND: Over 70% of Americans regularly experience stress. Chronic stress results in cancer, cardiovascular disease, depression, and diabetes, and thus is deeply detrimental to physiological health and psychological wellbeing. Developing robust m...
BMC medical informatics and decision making
Dec 30, 2020
BACKGROUND: Natural language processing (NLP) tools can facilitate the extraction of biomedical concepts from unstructured free texts, such as research articles or clinical notes. The NLP software tools CLAMP, cTAKES, and MetaMap are among the most w...
BMC medical informatics and decision making
Dec 30, 2020
BACKGROUND: The collection and examination of social media has become a useful mechanism for studying the mental activity and behavior tendencies of users. Through the analysis of a collected set of Twitter data, a model will be developed for predict...
BMC medical informatics and decision making
Dec 30, 2020
BACKGROUND: Age and time information stored within the histories of clinical notes can provide valuable insights for assessing a patient's disease risk, understanding disease progression, and studying therapeutic outcomes. However, details of age and...
Aging is emerging as a druggable target with growing interest from academia, industry and investors. New technologies such as artificial intelligence and advanced screening techniques, as well as a strong influence from the industry sector may lead t...
BACKGROUND: Personalized cancer vaccines are emerging as one of the most promising approaches to immunotherapy of advanced cancers. However, only a small proportion of the neoepitopes generated by somatic DNA mutations in cancer cells lead to tumor r...
BACKGROUND: Drug resistance is a critical problem limiting effective antiviral therapy for HIV/AIDS. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques...
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Dec 29, 2020
OBJECTIVE: Overnight high-dose dexamethasone suppression test (ON-HDDST) is a simple test to localize the source of ACTH in patients with ACTH-dependent Cushing's syndrome (CS). However, previous studies have reported its varying accuracy. We studied...
PURPOSE: The role of tumor-infiltrating lymphocytes (TILs) in predicting lymph node metastasis (LNM) in patients with T1 colorectal cancer (CRC) remains unclear. Furthermore, clinical utility of a machine learning-based approach has not been widely s...
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