Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Sep 9, 2020
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease with periods of flares and remission. Designing personalized treatment strategies for AD is challenging, given the apparent unpredictability and large variation in AD symptoms ...
Journal of chemical information and modeling
Sep 9, 2020
Artificial intelligence and multiobjective optimization represent promising solutions to bridge chemical and biological landscapes by addressing the automated design of compounds as a result of a humanlike creative process. In the present study, we ...
The SPIRIT 2013 statement aims to improve the completeness of clinical trial protocol reporting by providing evidence-based recommendations for the minimum set of items to be addressed. This guidance has been instrumental in promoting transparent eva...
The CONSORT 2010 statement provides minimum guidelines for reporting randomised trials. Its widespread use has been instrumental in ensuring transparency in the evaluation of new interventions. More recently, there has been a growing recognition that...
OBJECTIVE: In machine learning, it is evident that the classification of the task performance increases if bootstrap aggregation (bagging) is applied. However, the bagging of deep neural networks takes tremendous amounts of computational resources an...
Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), increase type 2 diabetes ris...
Proteins sample a variety of conformations distinct from their crystal structure. These structures, their propensities, and the pathways for moving between them contain an enormous amount of information about protein function that is hidden from a pu...
In this work, we show that a late fusion approach to multimodality in sign language recognition improves the overall ability of the model in comparison to the singular approaches of image classification (88.14%) and Leap Motion data classification (7...
International journal of environmental research and public health
Sep 9, 2020
The activity pattern is a significant factor in identifying hotspots of personal exposure to air pollutants, such as PM. However, the recording process of an activity pattern can be annoying to study participants, because they are often asked to brin...
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