AIMC Topic: Hydrogels

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Hydrogel delivery systems in intervertebral disc degeneration: Current status and future perspectives.

Journal of controlled release : official journal of the Controlled Release Society
Intervertebral disc degeneration (IVDD) is a primary contributor to the development of low back pain, characterized by core pathological features which include extracellular matrix (ECM) degradation, oxidative stress, imbalanced inflammatory microenv...

Smartphone-based fluorescence Eu/Ce-MOFs hydrogel sensor for sensitive and visual detection of tetracyclines with machine learning-assistance.

Food chemistry
The excessive use of tetracyclines (TCs) poses a significant threat to human health, necessitating the development of convenient, rapid, and intelligent detection methods for monitoring TCs residues in food products. In this work, we present a hetero...

Wearable Double Network Plasmonic Hydrogel for SERS Detection of Urea and Uric Acid in Sweat.

ACS sensors
Traditional wearable devices for sweat detection often face limitations such as low detection sensitivity, insufficient mechanical properties, and discomfort during use. To address these challenges, hydrogels are utilized as sensor patches to improve...

Advanced biomaterials in immune modulation: The future of regenerative therapies.

International journal of pharmaceutics
Healing of tissue is a complex process controlled by immune responses in the forms of inflammatory, proliferative, and remodeling stages. Dysregulated immunity can interfere with healing and lead to fibrosis or chronic inflammation. Biomaterials engi...

Liposome-encapsulated AICAR hydrogel regulates macrophage metabolic reprogramming via SIK1 activation to alleviate osteoarthritis.

Journal of nanobiotechnology
BACKGROUND: Osteoarthritis (OA), the most prevalent joint disorder, is characterized by a complex etiology and a lack of safe and effective therapeutic interventions. Emerging evidence suggests that immune cell dysregulation plays a pivotal role in t...

Self-assembling peptide hydrogels: design, mechanisms, characterization, and biomedical applications.

Soft matter
Self-assembled peptide hydrogels have emerged as a research frontier in biomedical engineering due to their exceptional water-retention capacity and spatiotemporal drug release kinetics. Researchers can fabricate biomaterials with customizable struct...

Magnetic-Driven Hydrogel Robots Loaded with Mitomycin for Active Therapy of Bladder Cancer.

ACS applied materials & interfaces
Intravesical drug instillation is a common treatment for bladder cancer, but it suffers from poor targeting and suboptimal patient experience due to the influence of gravity. Here, we innovatively designed a bladder cancer treatment method using sodi...

Multimodal information structuring with single-layer soft skins and high-density electrical impedance tomography.

Science robotics
The human skin can reliably capture a wide range of multimodal data over a large surface while providing a soft interface. Artificial technologies using microelectromechanical systems (MEMS) can emulate these biological functions but present numerous...

In situ foliar augmentation of multiple species for optical phenotyping and bioengineering using soft robotics.

Science robotics
Precision agriculture aims to increase crop yield while reducing the use of harmful chemicals, such as pesticides and excess fertilizer, using minimal, tailored interventions. However, these strategies are limited by factors such as sensor quality, w...

Tyramide signal amplification for a highly sensitive multiplex immunoassay based on encoded hydrogel microparticles.

The Analyst
Proteins play a crucial role as mediators of immune regulation, homeostasis, and metabolism, making their quantification essential for understanding disease mechanisms in biomedical research and clinical diagnostics. However, conventional methods whe...