Background Hyperpolarized noble gas MRI helps measure lung ventilation, but clinical translation remains limited. Free-breathing proton MRI may help quantify lung function using existing MRI systems without contrast material and may assist in providi...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2020
Histological Gleason grading of tumor patterns is one of the most powerful prognostic predictors in prostate cancer. However, manual analysis and grading performed by pathologists are typically subjective and time-consuming. In this paper, we present...
IEEE journal of biomedical and health informatics
Dec 4, 2020
The choroid provides oxygen and nourishment to the outer retina thus is related to the pathology of various ocular diseases. Optical coherence tomography (OCT) is advantageous in visualizing and quantifying the choroid in vivo. However, its applicati...
IEEE journal of biomedical and health informatics
Dec 4, 2020
Deep learning methods for diabetic retinopathy (DR) diagnosis are usually criticized as being lack of interpretability in the diagnostic result, thus limiting their application in clinic. Simultaneous prediction of DR related features during the DR s...
IEEE journal of biomedical and health informatics
Dec 4, 2020
Machine learning and especially deep learning techniques are dominating medical image and data analysis. This article reviews machine learning approaches proposed for diagnosing ophthalmic diseases during the last four years. Three diseases are addre...
IEEE journal of biomedical and health informatics
Dec 4, 2020
Image classification using convolutional neural networks (CNNs) outperforms other state-of-the-art methods. Moreover, attention can be visualized as a heatmap to improve the explainability of results of a CNN. We designed a framework that can generat...
IEEE journal of biomedical and health informatics
Dec 4, 2020
The direct analysis of 3D Optical Coherence Tomography (OCT) volumes enables deep learning models (DL) to learn spatial structural information and discover new bio-markers that are relevant to glaucoma. Downsampling 3D input volumes is the state-of-a...
IEEE journal of biomedical and health informatics
Dec 4, 2020
Neovascular age-related macular degeneration (nAMD) is nowadays successfully treated with anti-VEGF substances, but inter-individual treatment requirements are vastly heterogeneous and currently poorly plannable resulting in suboptimal treatment freq...
IEEE journal of biomedical and health informatics
Dec 4, 2020
As one of the most critical characteristics in advanced stage of non-exudative Age-related Macular Degeneration (AMD), Geographic Atrophy (GA) is one of the significant causes of sustained visual acuity loss. Automatic localization of retinal regions...
IEEE journal of biomedical and health informatics
Dec 4, 2020
Vascular structures in the retina contain important information for the detection and analysis of ocular diseases, including age-related macular degeneration, diabetic retinopathy and glaucoma. Commonly used modalities in diagnosis of these diseases ...
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