International journal of clinical and experimental pathology
Nov 1, 2015
We report one case of yolk sac tumor of the ear and review the literature. The patient was a 9-month boy who scratched his right ear repeatedly one month ago. Computed tomography scan showed an irregular elongated mass image measuring 42×16 mm was fo...
Generation of the primate cortex is characterized by the diversity of cortical precursors and the complexity of their lineage relationships. Recent studies have reported miscellaneous precursor types based on observer classification of cell biology f...
Laparoscopic resection of liver tumors located in the posterosuperior segments is a challenging operation that could be facilitated by robotic assistance. Laparoscopic resection of 12 tumors located in posterosuperior segments (IVa: 1; VII: 5; VIII: ...
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and ultimately fatal neurodegenerative disease, caused by the loss of motor neurons in the brain and spinal cord. Although 10% of ALS cases are familial (FALS), the majority are sporadic (S...
p53 immunohistochemistry (IHC) is widely used as a rapid surrogate for detecting mutations, with mutations being a key biomarker for poor outcomes in lymphomas. We developed two algorithms using digital quantification tools to assess p53 expression...
Archives of pathology & laboratory medicine
Aug 1, 2025
CONTEXT.—: Precise determination of biomarker status is necessary for clinical trial enrollment and endpoint analyses, as well as for optimal treatment determination in real-world practice. However, variabilities may be introduced into this process d...
CONTEXT: Staging cancer patients is crucial and requires analyzing all removed lymph nodes microscopically for metastasis. For this pivotal task, convolutional neural networks (CNN) can reduce workload and improve diagnostic accuracy.
Breast cancer is a significant global health concern, where precise identification of proteins like Human Epidermal Growth Factor Receptor 2 (HER2) in cancer cells via Immunohistochemistry (IHC) is pivotal for treatment decisions. HER2 overexpression...
Endometrioid adenocarcinoma (EA) has been on the increase in recent years in developed countries. Early detection of endometrioid adenocarcinoma in the endometrial corpus is crucial for patient prognosis and early treatment, although their distinctio...
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