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Immunohistochemistry

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Cell Counting and Segmentation of Immunohistochemical Images in the Spinal Cord: Comparing Deep Learning and Traditional Approaches.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Estimation of cell nuclei in images stained for the c-fos protein using immunohistochemistry (IHC) is infeasible in large image sets. Use of multiple human raters to increase throughput often creates variance in the data analysis. Machine learning te...

Population-Based Analysis of Histologically Confirmed Melanocytic Proliferations Using Natural Language Processing.

JAMA dermatology
IMPORTANCE: Population-based information on the distribution of histologic diagnoses associated with skin biopsies is unknown. Electronic medical records (EMRs) enable automated extraction of pathology report data to improve our epidemiologic underst...

Efficacy of eculizumab in an adult patient with HIV-associated hemolytic uremic syndrome: A case report.

Medicine
INTRODUCTION: Hemolytic uremic syndrome (HUS) in Human Immunodeficiency Virus (HIV)-positive patients has become a rare cause of kidney injury since the era of highly active antiretroviral therapy (HAART). Plasma exchange and antiretroviral therapy w...

Highly sensitive detection of human cancer antigens by an immunogold-silver assay chip coupled with a polythiophene-based optical sensor.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
This work presents a novel method for protein or cancer antigen detection in clinical samples by an immunogold-silver assay microfluidic biochip coupled with a polythiophene-based organic photodetector. The method has showed a detection limit below 1...