AIMC Topic: Ischemic Stroke

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Single-cell omics: moving towards a new era in ischemic stroke research.

European journal of pharmacology
Ischemic stroke (IS) is a highly complex and heterogeneous disease involving multiple pathophysiological events. A better understanding of the pathophysiology of IS will enhance preventive, diagnostic and therapeutic strategies. Despite significant a...

Developing an Explainable Prognostic Model for Acute Ischemic Stroke: Combining Clinical and Inflammatory Biomarkers With Machine Learning.

Brain and behavior
BACKGROUND: Predicting the prognosis of patients with acute cerebral infarction (ACI) is crucial for clinical decision-making and personalized treatment. However, existing models often lack the comprehensive integration of clinical and biological ind...

Prediction of tissue and clinical thrombectomy outcome in acute ischaemic stroke using deep learning.

Brain : a journal of neurology
The advent of endovascular thrombectomy has significantly improved outcomes for stroke patients with intracranial large vessel occlusion, yet individual benefits can vary widely. As demand for thrombectomy rises and geographical disparities in stroke...

Prediction of post stroke depression with machine learning: A national multicenter cohort study.

Journal of psychiatric research
OBJECTIVE: Post-stroke depression (PSD) is a common psychiatric complication following stroke, with low clinical detection rates and delayed diagnosis. Most existing PSD prediction models suffer from incomplete data inclusion, which limits their clin...

Two-stage convolutional neural network for segmentation and detection of carotid web on CT angiography.

Journal of neurointerventional surgery
BACKGROUND: Carotid web (CaW) is a risk factor for ischemic stroke, mainly in young patients with stroke of undetermined etiology. Its detection is challenging, especially among non-experienced physicians.

Development of a Diagnostic Prediction Model for Post-Stroke Cognitive Impairment in Acute Large Vessel Occlusion Stroke Using Multimodal MRI and PET/CT: A Study Protocol.

Brain and behavior
OBJECTIVE: Stroke is a leading cause of morbidity and disability worldwide. Post-stroke cognitive impairment (PSCI) significantly affects long-term prognosis in acute anterior circulation large-vessel occlusion stroke (LVO-AIS). This study aims to de...

Development of a deep neural network model for ultra-early neurological deterioration in ischemic stroke and analysis of associated risk factors.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
BACKGROUND: In this study, we established a deep neural network (DNN)-based predictive model, aiming to provide a basis for improving the treatment prognosis of early neurological deterioration (END) in patients with ultra-early ischemic stroke after...

Estimating individualized effectiveness of receiving successful recanalization for ischemic stroke cases using machine learning techniques.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
OBJECTIVES: Directly measuring the causal effect of mechanical thrombectomy (MT) for each ischemic stroke patient remains challenging, as it is impossible to observe the outcomes for both with and without successful recanalization in the same individ...