AIMC Topic: Lab-On-A-Chip Devices

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Advances in AI-assisted biochip technology for biomedicine.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
The integration of biochips with AI opened up new possibilities and is expected to revolutionize smart healthcare tools within the next five years. The combination of miniaturized, multi-functional, rapid, high-throughput sample processing and sensin...

Deep learning unlocks label-free viability assessment of cancer spheroids in microfluidics.

Lab on a chip
Despite recent advances in cancer treatment, refining therapeutic agents remains a critical task for oncologists. Precise evaluation of drug effectiveness necessitates the use of 3D cell culture instead of traditional 2D monolayers. Microfluidic plat...

GNN-Based Concentration Prediction With Variable Input Flow Rates for Microfluidic Mixers.

IEEE transactions on biomedical circuits and systems
Recent years have witnessed significant advances brought by microfluidic biochips in automating biochemical protocols. Accurate preparation of fluid samples is an essential component of these protocols, where concentration prediction and generation a...

Screening for urothelial carcinoma cells in urine based on digital holographic flow cytometry through machine learning and deep learning methods.

Lab on a chip
The incidence of urothelial carcinoma continues to rise annually, particularly among the elderly. Prompt diagnosis and treatment can significantly enhance patient survival and quality of life. Urine cytology remains a widely-used early screening meth...

Combining deep learning and droplet microfluidics for rapid and label-free antimicrobial susceptibility testing of colistin.

Biosensors & bioelectronics
Efficient tools for rapid antibiotic susceptibility testing (AST) are crucial for appropriate use of antibiotics, especially colistin, which is now often considered a last resort therapy with extremely drug resistant Gram-negative bacteria. Here, we ...

Multicolor-Assay-on-a-Chip Processed by Robotic Operation (MACpro) with Improved Diagnostic Accuracy for Field-Deployable Detection.

Analytical chemistry
The ability to deploy decentralized laboratories with autonomous and reliable disease diagnosis holds the potential to deliver accessible healthcare services for public safety. While microfluidic technologies provide precise manipulation of small flu...

AI-enhanced biomedical micro/nanorobots in microfluidics.

Lab on a chip
Human beings encompass sophisticated microcirculation and microenvironments, incorporating a broad spectrum of microfluidic systems that adopt fundamental roles in orchestrating physiological mechanisms. recapitulation of human microenvironments bas...

Human Motor System-Based Biohybrid Robot-On-a-Chip for Drug Evaluation of Neurodegenerative Disease.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Biohybrid robots have been developed for biomedical applications and industrial robotics. However, the biohybrid robots have limitations to be applied in neurodegenerative disease research due to the absence of a central nervous system. In addition, ...

Neural network execution using nicked DNA and microfluidics.

PloS one
DNA has been discussed as a potential medium for data storage. Potentially it could be denser, could consume less energy, and could be more durable than conventional storage media such as hard drives, solid-state storage, and optical media. However, ...

Blood quality evaluation on-chip classification of cell morphology using a deep learning algorithm.

Lab on a chip
The quality of red blood cells (RBCs) in stored blood has a direct impact on the recovery of patients treated by blood transfusion, which directly reflects the quality of blood. The traditional means for blood quality evaluation involve the use of re...