The complementary information found in different modalities of patient data can aid in more accurate modelling of a patient's disease state and a better understanding of the underlying biological processes of a disease. However, the analysis of multi...
Purpose To develop deep learning (DL) radiopathomics models based on contrast-enhanced MRI and pathologic imaging to predict vessels encapsulating tumor clusters (VETC) and survival in hepatocellular carcinoma (HCC). Materials and Methods In this ret...
Journal of the American College of Radiology : JACR
Mar 1, 2025
OBJECTIVE: Hepatocellular carcinoma (HCC) poses a heavy global disease burden; early diagnosis is critical to improve outcomes. Opportunistic screening-the use of imaging data acquired for other clinical indications for disease detection-as well as t...
Liver international : official journal of the International Association for the Study of the Liver
Mar 1, 2025
BACKGROUND & AIMS: Microvascular invasion (MVI) is associated with poor prognosis in hepatocellular carcinoma (HCC). Topology may improve the predictive performance and interpretability of deep learning (DL). We aimed to develop and externally valida...
BACKGROUND: Patients with early-stage hepatocellular carcinoma (HCC) generally have good survival rates following surgical resection. However, a subset of these patients experience recurrence within five years post-surgery.
BACKGROUND: Peritoneal metastasis (PM) after the rupture of hepatocellular carcinoma (HCC) is a critical issue that negatively affects patient prognosis. Machine learning models have shown great potential in predicting clinical outcomes; however, the...
Combinatorial chemistry & high throughput screening
Jan 1, 2025
BACKGROUND: Necroptosis, a recently identified mechanism of programmed cell death, exerts significant influence on various aspects of cancer biology, including tumor cell proliferation, stemness, metastasis, and immunosuppression. However, the role o...
Technology and health care : official journal of the European Society for Engineering and Medicine
Jan 1, 2025
BACKGROUND: Liver cancer poses a significant health challenge due to its high incidence rates and complexities in detection and treatment. Accurate segmentation of liver tumors using medical imaging plays a crucial role in early diagnosis and treatme...
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
Dec 30, 2024
Hepatocellular carcinoma (HCC) is a prevalent cancer that significantly contributes to mortality globally, primarily due to its late diagnosis. Early detection is crucial yet challenging. This study leverages the potential of deep learning (DL) techn...