In longitudinal observational studies with time-varying confounders, the generalized computation algorithm formula (g-formula) is a principled tool to estimate the average causal effect of a treatment regimen. However, the standard non-iterative g-fo...
Positron emission tomography (PET) imaging technology is widely used for diagnosing Alzheimer's disease (AD) in people with dementia. Although various computational methods have been proposed for diagnosis of AD using PET images, prediction of diseas...
BACKGROUND AND OBJECTIVES: Cortical lesions in multiple sclerosis (MS) severely affect cognition, but their longitudinal evolution and impact on specific cognitive functions remain understudied. This study investigates the evolution of function-speci...
Current care in multiple sclerosis (MS) primarily relies on infrequently obtained data such as magnetic resonance imaging, clinical laboratory tests or clinical history, resulting in subtle changes that may occur between visits being missed. Mobile t...
BACKGROUND: The incidence of cardiovascular metabolic diseases (CMD) continues to rise among middle-aged and elderly populations, affecting not only physical health but also significantly increasing the risk of depression. This study aims to construc...
Pain is common in middle-aged and older adults, has also been identified as a fall risk factor, whereas the mechanism of falls in pain is unclear. This study included 13,074 middle-aged and older adults from the China health and retirement longitudin...
INTRODUCTION: Deep brain stimulation (DBS) is a proven effective treatment for Parkinson's disease (PD). However, titrating DBS stimulation parameters is a labourious process and requires frequent hospital visits. Additionally, its current applicatio...
Studies in health technology and informatics
May 15, 2025
Chemotherapy toxicity can lead to acute hospital admissions, negatively impacting the healthcare system and patients' well-being. Machine learning (ML) models identifying patients at risk of emergency admissions are often developed on data lacking pa...
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