AIMC Topic: Lung Neoplasms

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Systems Biology and Machine Learning Identify Genetic Overlaps Between Lung Cancer and Gastroesophageal Reflux Disease.

Omics : a journal of integrative biology
One Health and planetary health place emphasis on the common molecular mechanisms that connect several complex human diseases as well as human and planetary ecosystem health. For example, not only lung cancer (LC) and gastroesophageal reflux disease ...

Predicting invasion in early-stage ground-glass opacity pulmonary adenocarcinoma: a radiomics-based machine learning approach.

BMC medical imaging
BACKGROUND: To design a pulmonary ground-glass nodules (GGN) classification method based on computed tomography (CT) radiomics and machine learning for prediction of invasion in early-stage ground-glass opacity (GGO) pulmonary adenocarcinoma.

Integrating multi-omics and machine learning survival frameworks to build a prognostic model based on immune function and cell death patterns in a lung adenocarcinoma cohort.

Frontiers in immunology
INTRODUCTION: The programmed cell death (PCD) plays a key role in the development and progression of lung adenocarcinoma. In addition, immune-related genes also play a crucial role in cancer progression and patient prognosis. However, further studies...

Multimodal radiomics-based methods using deep learning for prediction of brain metastasis in non-small cell lung cancer withF-FDG PET/CT images.

Biomedical physics & engineering express
. Approximately 57% of non-small cell lung cancer (NSCLC) patients face a 20% risk of brain metastases (BMs). The delivery of drugs to the central nervous system is challenging because of the blood-brain barrier, leading to a relatively poor prognosi...

Developing an ensemble machine learning study: Insights from a multi-center proof-of-concept study.

PloS one
BACKGROUND: To address the numerous unmeet clinical needs, in recent years several Machine Learning models applied to medical images and clinical data have been introduced and developed. Even when they achieve encouraging results, they lack evolution...

Artificial intelligence system for identification of overlooked lung metastasis in abdominopelvic computed tomography scans of patients with malignancy.

Diagnostic and interventional radiology (Ankara, Turkey)
PURPOSE: This study aimed to evaluate whether an artificial intelligence (AI) system can identify basal lung metastatic nodules examined using abdominopelvic computed tomography (CT) that were initially overlooked by radiologists.

Implementing machine learning to predict survival outcomes in patients with resected pulmonary large cell neuroendocrine carcinoma.

Expert review of anticancer therapy
BACKGROUND: The post-surgical prognosis for Pulmonary Large Cell Neuroendocrine Carcinoma (PLCNEC) patients remains largely unexplored. Developing a precise prognostic model is vital to assist clinicians in patient counseling and creating effective t...

Development of a prognostic model for NSCLC based on differential genes in tumour stem cells.

Scientific reports
Non-small cell lung cancer (NSCLC) constitutes a significant portion of lung cancers and cytotoxic drugs (e.g. cisplatin) are currently the first-line treatment. However, NSCLC has developed resistance to this drug, which limits the therapeutic effec...

Combining Multistaged Filters and Modified Segmentation Network for Improving Lung Nodules Classification.

IEEE journal of biomedical and health informatics
Advancements in computational technology have led to a shift towards automated detection processes in lung cancer screening, particularly through nodule segmentation techniques. These techniques employ thresholding to distinguish between soft and fir...

Computer-aided diagnosis for lung cancer using waterwheel plant algorithm with deep learning.

Scientific reports
Lung cancer (LC) is a life-threatening and dangerous disease all over the world. However, earlier diagnoses and treatment can save lives. Earlier diagnoses of malevolent cells in the lungs responsible for oxygenating the human body and expelling carb...