AIMC Topic: Lymphocytes

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Comparison of MPL-ANN and PLS-DA models for predicting the severity of patients with acute pancreatitis: An exploratory study.

The American journal of emergency medicine
OBJECTIVE: Acute pancreatitis (AP) is a common inflammatory disorder that may develop into severe AP (SAP), resulting in life-threatening complications and even death. The purpose of this study was to explore two different machine learning models of ...

A rapid white blood cell classification system based on multimode imaging technology.

Journal of biophotonics
In order to simplify the complexity of white blood cell classification in existing point-of-care testing (POCT) testing equipment, a white blood cell classification detection system based on microfluidic and multimode imaging was constructed. Microfl...

Improved Classification of White Blood Cells with the Generative Adversarial Network and Deep Convolutional Neural Network.

Computational intelligence and neuroscience
White blood cells (leukocytes) are a very important component of the blood that forms the immune system, which is responsible for fighting foreign elements. The five types of white blood cells include , , , , and , where each type constitutes a diffe...

Purification of viable peripheral blood mononuclear cells for biobanking using a robotized liquid handling workstation.

Journal of translational medicine
BACKGROUND: The purification of peripheral blood mononuclear cells (PBMCs) by means of density gradient (1.07 g/mL) centrifugation is one of the most commonly used methods in diagnostics and research laboratories as well as in biobanks. Here, we eval...

Classification of DNA damages on segmented comet assay images using convolutional neural network.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Identification and quantification of DNA damage is a very significant subject in biomedical research area which still needs more robust and effective methods. One of the cheapest, easy to use and most successful method for D...

White blood cells detection and classification based on regional convolutional neural networks.

Medical hypotheses
White blood cells (WBC) are important parts of our immune system and they protect our body against infections by eliminating viruses, bacteria, parasites and fungi. There are five types of WBC. These are called Lymphocytes, Monocytes, Eosinophils, Ba...

Learning to detect lymphocytes in immunohistochemistry with deep learning.

Medical image analysis
The immune system is of critical importance in the development of cancer. The evasion of destruction by the immune system is one of the emerging hallmarks of cancer. We have built a dataset of 171,166 manually annotated CD3 and CD8 cells, which we us...

From Discrete to Continuous Modeling of Lymphocyte Development and Plasticity in Chronic Diseases.

Frontiers in immunology
The molecular events leading to differentiation, development, and plasticity of lymphoid cells have been subject of intense research due to their key roles in multiple pathologies, such as lymphoproliferative disorders, tumor growth maintenance and c...

Convolutional Neural Networks for Recognition of Lymphoblast Cell Images.

Computational intelligence and neuroscience
This paper presents the recognition for WHO classification of acute lymphoblastic leukaemia (ALL) subtypes. The two ALL subtypes considered are T-lymphoblastic leukaemia (pre-T) and B-lymphoblastic leukaemia (pre-B). They exhibit various characterist...

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning.

Journal of visualized experiments : JoVE
We describe here a protocol for the label-free identification of lymphocyte subtypes using quantitative phase imaging and machine learning. Identification of lymphocyte subtypes is important for the study of immunology as well as diagnosis and treatm...