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Lymphocytes

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White blood cells detection and classification based on regional convolutional neural networks.

Medical hypotheses
White blood cells (WBC) are important parts of our immune system and they protect our body against infections by eliminating viruses, bacteria, parasites and fungi. There are five types of WBC. These are called Lymphocytes, Monocytes, Eosinophils, Ba...

Classification of DNA damages on segmented comet assay images using convolutional neural network.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Identification and quantification of DNA damage is a very significant subject in biomedical research area which still needs more robust and effective methods. One of the cheapest, easy to use and most successful method for D...

Improved Classification of White Blood Cells with the Generative Adversarial Network and Deep Convolutional Neural Network.

Computational intelligence and neuroscience
White blood cells (leukocytes) are a very important component of the blood that forms the immune system, which is responsible for fighting foreign elements. The five types of white blood cells include , , , , and , where each type constitutes a diffe...

A rapid white blood cell classification system based on multimode imaging technology.

Journal of biophotonics
In order to simplify the complexity of white blood cell classification in existing point-of-care testing (POCT) testing equipment, a white blood cell classification detection system based on microfluidic and multimode imaging was constructed. Microfl...

A Machine Learning Tool Using Digital Microscopy (Morphogo) for the Identification of Abnormal Lymphocytes in the Bone Marrow.

Acta cytologica
Morphological analysis of the bone marrow is an essential step in the diagnosis of hematological disease. The conventional analysis of bone marrow smears is performed under a manual microscope, which is labor-intensive and subject to interobserver va...

Comparison of MPL-ANN and PLS-DA models for predicting the severity of patients with acute pancreatitis: An exploratory study.

The American journal of emergency medicine
OBJECTIVE: Acute pancreatitis (AP) is a common inflammatory disorder that may develop into severe AP (SAP), resulting in life-threatening complications and even death. The purpose of this study was to explore two different machine learning models of ...

Correlation between lung infection severity and clinical laboratory indicators in patients with COVID-19: a cross-sectional study based on machine learning.

BMC infectious diseases
BACKGROUND: Coronavirus disease 2019 (COVID-19) has caused a global pandemic that has raised worldwide concern. This study aims to investigate the correlation between the extent of lung infection and relevant clinical laboratory testing indicators in...

Tens of images can suffice to train neural networks for malignant leukocyte detection.

Scientific reports
Convolutional neural networks (CNNs) excel as powerful tools for biomedical image classification. It is commonly assumed that training CNNs requires large amounts of annotated data. This is a bottleneck in many medical applications where annotation r...

Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data.

Briefings in bioinformatics
Single-cell RNA sequencing (scRNA-Seq) is an emerging strategy for characterizing immune cell populations. Compared to flow or mass cytometry, scRNA-Seq could potentially identify cell types and activation states that lack precise cell surface marker...