AIMC Topic: Lysine

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The Major Chromophore Arising from Glucose Degradation and Oxidative Stress Occurrence during Lens Proteins Glycation Induced by Glucose.

Molecules (Basel, Switzerland) Dec 22, 2017
Glucose autoxidation has been proposed as a key reaction associated with deleterious effects induced by hyperglycemia in the eye lens. Little is known about chromophores generated during glucose autoxidation. In this study, we analyzed the effect of ...
Animals Hydrogen Peroxide Cattle Oxidative Stress Glycosylation Oxidation-Reduction Crystallins Gluconates Pyruvaldehyde Glyoxal Lysine Solutions Lens, Crystalline Cations, Divalent Copper Glucose
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l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.

Nutrition research (New York, N.Y.) Nov 17, 2017
Considering the pathologic importance of metabolic disturbances, advanced glycation end products (AGEs), and chronic inflammation in diabetes mellitus and ameliorating potentials of l-carnosine in hampering these detritions and because these effects ...
Carnosine Arginine Triglycerides Lysine Humans Glycation End Products, Advanced Tumor Necrosis Factor-alpha Double-Blind Method Female Body Composition Adult Glycated Hemoglobin Blood Glucose Male Diabetes Mellitus, Type 2 Middle Aged Dietary Supplements Fasting Adipose Tissue
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Glypre: In Silico Prediction of Protein Glycation Sites by Fusing Multiple Features and Support Vector Machine.

Molecules (Basel, Switzerland) Nov 3, 2017
Glycation is a non-enzymatic process occurring inside or outside the host body by attaching a sugar molecule to a protein or lipid molecule. It is an important form of post-translational modification (PTM), which impairs the function and changes the ...
Algorithms Computer Simulation Sensitivity and Specificity Area Under Curve ROC Curve Glycosylation Amino Acids Support Vector Machine Lysine Proteins Binding Sites
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Predicting lysine glycation sites using bi-profile bayes feature extraction.

Computational biology and chemistry Oct 12, 2017
Glycation is a nonenzymatic post-translational modification which has been found to be involved in various biological processes and closely associated with many metabolic diseases. The accurate identification of glycation sites is important to unders...
Bayes Theorem Internet Lysine Computational Biology Glycosylation Support Vector Machine
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Enhanced d-tagatose production by spore surface-displayed l-arabinose isomerase from isolated Lactobacillus brevis PC16 and biotransformation.

Bioresource technology Oct 3, 2017
In the present study, a new strain of Lactobacillus brevis producing d-tagatose was isolated and identified. Then, the l-arabinose isomerase (L-AI) of this strain was displayed on the spore surface of Bacillus subtilis DB403 by using an anchoring pro...
Levilactobacillus brevis Galactose Lysine Biotransformation 4-Chloro-7-nitrobenzofurazan Aldose-Ketose Isomerases Hexoses Spores, Bacterial
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Prediction of CML contents in the Maillard reaction products for casein-monosaccharides model.

Food chemistry Jul 27, 2017
Response surface methodology (RSM) was applied to predict the processing parameters of the casein-glucose/galactose Maillard reaction (MR) for determining the level of N-(1-carboxymethyl)-l-lysine (CML), one of the typically harmful dietary advanced ...
Electrophoresis, Polyacrylamide Gel Glycation End Products, Advanced Maillard Reaction Temperature Monosaccharides Reactive Oxygen Species Caseins Microscopy, Electron, Transmission Lysine
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Prediction of lysine propionylation sites using biased SVM and incorporating four different sequence features into Chou's PseAAC.

Journal of molecular graphics & modelling Jul 25, 2017
Lysine propionylation is an important and common protein acylation modification in both prokaryotes and eukaryotes. To better understand the molecular mechanism of propionylation, it is important to identify propionylated substrates and their corresp...
Amino Acid Sequence Computational Biology Acetylation Support Vector Machine Lysine Algorithms Protein Processing, Post-Translational Position-Specific Scoring Matrices Reproducibility of Results Amino Acids Peptides
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Identify and analysis crotonylation sites in histone by using support vector machines.

Artificial intelligence in medicine Mar 7, 2017
OBJECTIVE: Lysine crotonylation (Kcr) is a newly discovered histone posttranslational modification, which is specifically enriched at active gene promoters and potential enhancers in mammalian cell genomes. Although lysine crotonylation sites can be ...
Humans Reproducibility of Results Animals Mice Databases, Protein Amino Acid Sequence Lysine Histones Computational Biology Support Vector Machine Protein Processing, Post-Translational
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Positive-Unlabeled Learning for Pupylation Sites Prediction.

BioMed research international Aug 7, 2016
Pupylation plays a key role in regulating various protein functions as a crucial posttranslational modification of prokaryotes. In order to understand the molecular mechanism of pupylation, it is important to identify pupylation substrates and sites ...
Binding Sites Ubiquitination Proteins Databases, Protein Lysine Machine Learning Algorithms Support Vector Machine Protein Processing, Post-Translational
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Predicting lysine phosphoglycerylation with fuzzy SVM by incorporating k-spaced amino acid pairs into Chou׳s general PseAAC.

Journal of theoretical biology Feb 22, 2016
As a new type of post-translational modification, lysine phosphoglycerylation plays a key role in regulating glycolytic process and metabolism in cells. Due to the traditional experimental methods are time-consuming and labor-intensive, it is importa...
Lysine Binding Sites Diphosphoglyceric Acids Reproducibility of Results Computational Biology Support Vector Machine Fuzzy Logic Protein Processing, Post-Translational Amino Acids Amino Acid Sequence Software Algorithms
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