International journal of pharmaceutics
Jul 23, 2025
Misuse and poor inhalation techniques remain persistent issues in pulmonary drug delivery via dry powder inhalation. While acoustic-based monitoring has been a feasible strategy, existing approaches often depend on smartphones for signal collection, ...
Although pesticide application is indispensable for agricultural productivity, improper use can pose significant health risks, particularly for vulnerable populations. This study investigated the effects of pesticide exposure on metabolic pathways an...
International journal of biological macromolecules
Jul 23, 2025
Targeting distal mutations holds promising implications for enzyme engineering. Here, we present an open-source computational workflow designed to explore the functional impact of distal sites, demonstrated on an artificial enzyme built on the widely...
The global shortage of mental health services has sparked considerable interest in leveraging generative artificial intelligence (AI) to address psychological health challenges. This study systematically evaluates the emotional support capabilities o...
BACKGROUND: Traumatic brain injury (TBI) is among the most prevalent causes of emergency department visits globally. TBI leads to high morbidity and mortality rates, which poses a noteworthy burden on the medical system regarding both patients and ec...
Coronavirus disease 2019 (COVID-19), a global pandemic infectious disease, requires early diagnosis and dynamic monitoring to enable timely intervention and reduce the risks of adverse outcomes. To support these needs, we developed an advanced metabo...
Pervasive antibiotic pollution in water environments has emerged as a serious threat to global ecosystem functions and public health. While wetland expansion─including protection, restoration, and construction, is widely promoted for sustainable wate...
Accurate estimation of the postmortem interval (PMI) is crucial for medico-legal investigations, providing critical timelines for criminal cases. Current PMI methods, however, often lack precision, limiting their forensic utility. In this study, we d...
Accurate protein expression in human immune cells is essential for appropriate cellular function. The mechanisms that define protein abundance are complex and are executed on transcriptional, posttranscriptional, and posttranslational levels. Here, w...
BACKGROUND: Limited research has been conducted on the prevalence of acute kidney injury (AKI) and acute kidney disease (AKD) in gout patients, as well as the impact of these renal complications on patient outcomes. This study aims to develop machine...
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