AIMC Topic: Machine Learning

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Predicting infections with multidrug-resistant organisms (MDROs) in neurocritical care patients with hospital-acquired pneumonia (HAP): development of a novel multivariate prediction model.

Microbiology spectrum
Hospital-acquired pneumonia (HAP) is prevalent in the neuro-intensive care unit (NICU), significantly increasing susceptibility to infections with multidrug-resistant organisms (MDROs), which result in high mortality rates and substantial healthcare ...

Distinguishing critical microbial community shifts from normal temporal variability in human and environmental ecosystems.

Scientific reports
Differentiating significant microbial community changes from normal fluctuations is vital for understanding microbial dynamics in human and environmental ecosystems. This knowledge could enable early warning systems to monitor critical changes affect...

QSPR analysis of physico-chemical and pharmacological properties of medications for Parkinson's treatment utilizing neighborhood degree-based topological descriptors.

Scientific reports
Topological indices are invariant quantitative metrics associated with a molecular graph, which characterize the bonding topology of a molecule. The main aim of analyzing topological indices is to summarize and transform chemical structural informati...

Reinforcement Learning-Driven Path Generation for Ankle Rehabilitation Robot Using Musculoskeletal-Informed Energy Optimization.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
In rehabilitation robotics, optimizing energy consumption and high interaction forces is essential to prevent unnecessary muscle fatigue and excessive joint loading as they often cause an inefficient trajectory planning and disrupt natural movement p...

Gait Characteristics Associated with Walking Speed in Postoperative Patients with Adult Spinal Deformity Extracted by Machine Learning.

Annals of biomedical engineering
PURPOSE: Patients with adult spinal deformity (ASD) are unable to walk faster even after spinal fixation. Gait rehabilitation that focuses on movements associated with reduced speed may help improve gait function. This study aimed to identify the gai...

Unraveling potent Glycyrrhiza glabra flavonoids as AKT1 inhibitors using network pharmacology and machine learning-assisted QSAR.

Molecular diversity
Glycyrrhiza glabra (G. glabra) phytocompounds have been reported to interact with neurological targets, including those implicated in epilepsy, and may modulate epilepsy-related targets. While substantial evidence supports their potential antiepilept...

Combining lipidomics and machine learning to identify lipid biomarkers for nonsyndromic cleft lip with palate.

JCI insight
Nonsyndromic cleft lip with palate (nsCLP) is a common birth defect disease. Current diagnostic methods comprise fetal ultrasound images, which are mainly limited by fetal position and technician skills. We aimed to identify reliable maternal serum l...

Enhancing clinical decision-making in closed pelvic fractures with machine learning models.

Biomolecules & biomedicine
Closed pelvic fractures can lead to severe complications, including hemodynamic instability (HI) and mortality. Accurate prediction of these risks is crucial for effective clinical management. This study aimed to utilize various machine learning (ML)...

Comparison of Machine Learning Algorithms and Bayesian Estimation in Predicting Tacrolimus Concentration in Tunisian Kidney Transplant Patients During the Early Post-Transplant Period.

European journal of drug metabolism and pharmacokinetics
BACKGROUND AND OBJECTIVE: Model-informed precision dosing (MIPD), based on a Bayesian approach and machine learning (ML) algorithms, is a suitable approach to personalize dosage recommendations and to improve the concentration target attainment for e...

Radiomic analysis based on machine learning of multi-sequences MR to assess early treatment response in locally advanced nasopharyngeal carcinoma.

Science progress
ObjectiveThe prediction of early response in locally advanced nasopharyngeal carcinoma (LA-NPC) after concurrent chemoradiotherapy (CCRT) is important for determining the need for timely consolidation therapy. We developed a radiomic analysis of mult...