AIMC Topic: Machine Learning

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Computational Approaches as Rational Decision Support Systems for Discovering Next-Generation Antitubercular Agents: Mini-Review.

Current computer-aided drug design
Tuberculosis, malaria, dengue, chikungunya, leishmaniasis etc. are a large group of neglected tropical diseases that prevail in tropical and subtropical countries, affecting one billion people every year. Minimal funding and grants for research on th...

Constructing a Risk Prediction Model for Lung Cancer Recurrence by Using Gene Function Clustering and Machine Learning.

Combinatorial chemistry & high throughput screening
OBJECTIVE: A significant proportion of patients with early non-small cell lung cancer (NSCLC) can be cured by surgery. The distant metastasis of tumors is the most common cause of treatment failure. Precisely predicting the likelihood that a patient ...

Machine learning in multiexposure laser speckle contrast imaging can replace conventional laser Doppler flowmetry.

Journal of biomedical optics
Laser speckle contrast imaging (LSCI) enables video rate imaging of blood flow. However, its relation to tissue blood perfusion is nonlinear and depends strongly on exposure time. By contrast, the perfusion estimate from the slower laser Doppler flow...

Recent Progress in Machine Learning-based Prediction of Peptide Activity for Drug Discovery.

Current topics in medicinal chemistry
Over the past decades, peptide as a therapeutic candidate has received increasing attention in drug discovery, especially for antimicrobial peptides (AMPs), anticancer peptides (ACPs) and antiinflammatory peptides (AIPs). It is considered that the pe...

Adverse Drug Event Detection from Electronic Health Records Using Hierarchical Recurrent Neural Networks with Dual-Level Embedding.

Drug safety
INTRODUCTION: Adverse drug event (ADE) detection is a vital step towards effective pharmacovigilance and prevention of future incidents caused by potentially harmful ADEs. The electronic health records (EHRs) of patients in hospitals contain valuable...

[Artificial Intelligence in Psychiatry].

Brain and nerve = Shinkei kenkyu no shinpo
Diagnosis of psychiatric disorders is based primarily on subjective symptoms, and neuroimaging or other biological examinations are used for excluding organic disorders. Advances in artificial intelligence technologies, such as machine learning, may ...

MADEx: A System for Detecting Medications, Adverse Drug Events, and Their Relations from Clinical Notes.

Drug safety
INTRODUCTION: Early detection of adverse drug events (ADEs) from electronic health records is an important, challenging task to support pharmacovigilance and drug safety surveillance. A well-known challenge to use clinical text for detection of ADEs ...