BACKGROUND: Tibial intramedullary nailing (IMN) represents a standard treatment for fractures of the tibial shaft. Nevertheless, accurately predicting the appropriate nail length prior to surgery remains a challenging endeavour. Conventional techniqu...
OBJECTIVE: To develop an interpretable machine learning (ML) model for predicting severe Mycoplasma pneumoniae pneumonia (SMPP) in order to provide reliable factors for predicting the clinical type of the disease.
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a severe complication associated with a high mortality rate in patients with sepsis. Early identification of patients with sepsis at high risk of developing ARDS is crucial for timely interven...
Multiple machine learning techniques were employed to identify key long non-coding RNA (lncRNA) biomarkers associated with cuproptosis in Diffuse Large B-Cell Lymphoma (DLBCL). Data from the TCGA and GEO databases facilitated the identification of 12...
This research assesses multiple predictive models aimed at estimating disintegration time for pharmaceutical oral formulations, based on a dataset comprising nearly 2,000 data points that include molecular, physical, compositional, and formulation at...
Tuberculosis, a deadly and contagious disease caused by Mycobacterium tuberculosis, remains a significant global public health threat. HIV co-infection significantly increases the risk of active TB recurrence and prolongs medical treatment for tuberc...
Biological tissues exhibit complex gene expression and multicellular patterns that are valuable to dissect. Single-cell RNA sequencing (scRNA-seq) provides full coverages of genes, but lacks spatial information, whereas spatial transcriptomics (ST) m...
The design of proteins capable effectively binding to specific protein targets is crucial for developing therapies, diagnostics, and vaccine candidates for viral infections. Here, we introduce a complementarity-determining region (CDR) grafting appro...
Accurate assessment of training status in team sports is crucial for optimising performance and reducing injury risk. This pilot study investigates the feasibility of using machine learning (ML) models to estimate oxygen uptake (VO2) with wearable se...
American journal of Alzheimer's disease and other dementias
Apr 21, 2025
A growing body of literature has examined the impact of neighborhood characteristics on Alzheimer's disease (AD) dementia, yet the spatial variability and relative importance of the most influential factors remain underexplored. We compiled various w...
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