The spine journal : official journal of the North American Spine Society
Mar 26, 2025
BACKGROUND CONTEXT: When treating spinal metastases in a palliative setting, maintaining or enhancing quality of life (QoL) is the primary therapeutic objective. Clinicians tailor their treatment strategy by weighing the QoL benefits against expected...
OBJECTIVE: A report from the Canadian Institute for Health Information found unplanned hospital readmissions (UHR) common, costly, and potentially avoidable, estimating a $1.8 billion cost to the Canadian healthcare system associated with inpatient r...
Somatic mutations could influence critical cellular processes, leading to uncontrolled cell growth and tumor formation. Understanding the intricate interactions between somatic mutations and drugs was crucial for advancing our knowledge of the underl...
BACKGROUND: Current treatment paradigms assume aortic regurgitation (AR) patients to be a homogenous population, but varied courses of disease progression and outcomes are observed clinically.
Empowering intelligent robots with cognitive abilities that rival or even surpass those of humans is the key to enabling more complex and sophisticated interactions. Currently, most electronic skins (e-skins) perform excellently in distinguishing sha...
Analyzing the impacts of climate change (CC) and human activities (HA) on hydrological events is important for water resource management. This study quantifies the impacts of CC and HA on runoff and hydrological drought characteristics (HDC) in the Y...
PURPOSE: The human Ether-a-go-go Related-Gene (hERG) encodes rectifying potassium channels that play a significant role during action potential repolarization of cardiomyocytes. Blockade of the hERG channel by off-target drugs can lead to long QT syn...
BACKGROUND: Early detection of clinical deterioration using machine-learning early warning scores may improve outcomes. However, most implemented scores were developed using logistic regression, only underwent retrospective validation, and were not t...
This paper presents a terahertz metasurface based sensor design incorporating graphene and other plasmonic materials for highly sensitive detection of different chemicals. The proposed sensor employs the combination of multiple resonator designs - in...
Peptides are ubiquitous and important biomolecules that self-assemble into diverse structures. Although extensive research has explored the effects of chemical composition and exterior conditions on self-assembly, a systematic study consolidating the...
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