AIMC Topic: Machine Learning

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Predicting Risk for Patent Ductus Arteriosus in the Neonate: A Machine Learning Analysis.

Medicina (Kaunas, Lithuania)
: Patent ductus arteriosus (PDA) is common in newborns, being associated with high morbidity and mortality. While maternal and neonatal conditions are known contributors, few studies use advanced machine learning (ML) as predictive factors. This stud...

Machine Learning-Guided Screening and Molecular Docking for Proposing Naturally Derived Drug Candidates Against MERS-CoV 3CL Protease.

International journal of molecular sciences
In this study, we utilized machine learning techniques to identify potential inhibitors of the MERS-CoV 3CL protease. Among the models evaluated, the Random Forest (RF) algorithm exhibited the highest predictive performance, achieving an accuracy of ...

Physiological Sensor Modality Sensitivity Test for Pain Intensity Classification in Quantitative Sensory Testing.

Sensors (Basel, Switzerland)
Chronic pain is prevalent and disproportionately impacts adults with a lower quality of life. Although subjective self-reporting is the "gold standard" for pain assessment, tools are needed to objectively monitor and account for inter-individual diff...

Predicting rheumatoid arthritis progression from seronegative undifferentiated arthritis using machine learning: a deep learning model trained on the KURAMA cohort and externally validated with the ANSWER cohort.

Arthritis research & therapy
BACKGROUND: Undifferentiated arthritis (UA) often develops into rheumatoid arthritis (RA), but predicting disease progression from seronegative UA remains challenging because seronegative RA often does not meet the classification criteria. This study...

Interpretable machine learning method to predict the risk of pre-diabetes using a national-wide cross-sectional data: evidence from CHNS.

BMC public health
OBJECTIVE: The incidence of Type 2 Diabetes Mellitus (T2DM) continues to rise steadily, significantly impacting human health. Early prediction of pre-diabetic risks has emerged as a crucial public health concern in recent years. Machine learning meth...

Explainable AI for Symptom-Based Detection of Monkeypox: a machine learning approach.

BMC infectious diseases
BACKGROUND: Monkeypox, a viral zoonotic disease, is an emerging global health concern, with rising incidence and outbreaks extending beyond its endemic regions in Central and, West Africa and the world. The disease transmits through contact with infe...

Machine learning-based prognostic model for bloodstream infections in hematological malignancies using Th1/Th2 cytokines.

BMC infectious diseases
OBJECTIVE: Bloodstream infection (BSI) is a significant cause of mortality in patients with hematologic malignancies(HMs), particularly amid rising antibiotic resistance. This study aimed to analyze pathogen distribution, drug-resistance patterns and...

Resolving multi-image spatial lipidomic responses to inhaled toxicants by machine learning.

Nature communications
Regional responses to inhaled toxicants are essential to understand the pathogenesis of lung disease under exposure to air pollution. We evaluate the effect of combined allergen sensitization and ozone exposure on eliciting spatial differences in lip...

Integrating bioinformatics and machine learning for comprehensive analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in pediatric septic shock.

Scientific reports
This study aims to predict and diagnose pediatric septic shock through the screening of immune infiltration-related biomarkers. Three gene expression datasets were accessible from the Gene Expression Omnibus repository. The differentially expressed g...

Quantitative prediction of disinfectant tolerance in Listeria monocytogenes using whole genome sequencing and machine learning.

Scientific reports
Listeria monocytogenes is a potentially severe disease-causing bacteria mainly transmitted through food. This pathogen is of great concern for public health and the food industry in particular. Many countries have implemented thorough regulations, an...