AIMC Topic: Machine Learning

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Pseudo-HFOs Elimination in iEEG Recordings Using a Robust Residual-Based Dictionary Learning Framework.

IEEE journal of biomedical and health informatics
High-frequency oscillations (HFOs) in intracranial EEG (iEEG) recordings are critical biomarkers for localizing the seizure onset zone (SOZ) in patients with focal refractory epilepsy. Despite their clinical significance, HFO analysis is often compro...

Detecting Opioid Use Disorder in Health Claims Data With Positive Unlabeled Learning.

IEEE journal of biomedical and health informatics
Accurate detection and prevalence estimation of behavioral health conditions, such as opioid use disorder (OUD), are crucial for identifying at-risk individuals, determining treatment needs, monitoring prevention and intervention efforts, and recruit...

Prediction of the Extent of Blood-Brain Barrier Transport Using Machine Learning and Integration into the LeiCNS-PK3.0 Model.

Pharmaceutical research
INTRODUCTION: The unbound brain-to-plasma partition coefficient (K) is an essential parameter for predicting central nervous system (CNS) drug disposition using physiologically-based pharmacokinetic (PBPK) modeling. K values for specific compounds ar...

Comparing Phenotypes for Acute and Long-Term Response to Atrial Fibrillation Ablation Using Machine Learning.

Circulation. Arrhythmia and electrophysiology
BACKGROUND: It is difficult to identify patients with atrial fibrillation (AF) most likely to respond to ablation. While any arrhythmia patient may recur after acutely successful ablation, AF is unusual in that patients may have long-term arrhythmia ...

Machine Learning Identification and Classification of Mitosis and Migration of Cancer Cells in a Lab-on-CMOS Capacitance Sensing Platform.

IEEE journal of biomedical and health informatics
Cell culture assays play a vital role in various fields of biology. Conventional assay techniques like immunohistochemistry, immunofluorescence, and flow cytometry offer valuable insights into cell phenotype and behavior. However, each of these techn...

Incremental Classification for High-Dimensional EEG Manifold Representation Using Bidirectional Dimensionality Reduction and Prototype Learning.

IEEE journal of biomedical and health informatics
In brain-computer interface (BCI) systems, symmetric positive definite (SPD) manifold within Riemannian space has been frequently utilized to extract spatial features from electroencephalogram (EEG) signals. However, the intrinsic high dimensionality...

ADR-DQPU: A Novel ADR Signal Detection Using Deep Reinforcement and Positive-Unlabeled Learning.

IEEE journal of biomedical and health informatics
The medical community has grappled with the challenge of analysis and early detection of severe and unknown adverse drug reactions (ADRs) from Spontaneous Reporting Systems (SRSs) like the FDA Adverse Event Reporting System (FAERS), which often lack ...

EEG Temporal-Spatial Feature Learning for Automated Selection of Stimulus Parameters in Electroconvulsive Therapy.

IEEE journal of biomedical and health informatics
The risk of adverse effects in Electroconvulsive Therapy (ECT), such as cognitive impairment, can be high if an excessive stimulus is applied to induce the necessary generalized seizure (GS); Conversely, inadequate stimulus results in failure. Recent...

Partial Annotation Learning for Biomedical Entity Recognition.

IEEE journal of biomedical and health informatics
Named Entity Recognition (NER) is a key task to support biomedical research. In Biomedical Named Entity Recognition (BioNER), obtaining high-quality expert annotated data is laborious and expensive, leading to the development of automatic approaches ...

Predicting Clinical Anticancer Drug Response of Patients by Using Domain Alignment and Prototypical Learning.

IEEE journal of biomedical and health informatics
Anticancer drug response prediction is crucial in developing personalized treatment plans for cancer patients. However, High-quality patient anticancer drug response data are scarce and cell line data and patient data have different distributions, mo...