AIMC Topic: Machine Learning

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A machine learning-based model for predicting paroxysmal and persistent atrial fibrillation based on EHR.

BMC medical informatics and decision making
BACKGROUND: There is no effective way to accurately predict paroxysmal and persistent atrial fibrillation (AF) subtypes unless electrocardiogram (ECG) observation is obtained. We aim to develop a predictive model using a machine learning algorithm fo...

Prediction of the Risk of Adverse Clinical Outcomes with Machine Learning Techniques in Patients with Noncommunicable Diseases.

Journal of medical systems
Decision-making in chronic diseases guided by clinical decision support systems that use models including multiple variables based on artificial intelligence requires scientific validation in different populations to optimize the use of limited human...

Machine Learning-Based Prediction of Drug Solubility in Lipidic Environments: The Sol_ME Tool for Optimizing Lipid-Based Formulations with a Preliminary Apalutamide Case Study.

AAPS PharmSciTech
Lipid-based formulations are essential for enhancing drug solubility and bioavailability, yet selecting optimal lipid excipients for specific drugs remains challenging. This study introduces Sol_ME, a machine learning-based model designed to predict ...

Deep learning and radiomics for gastric cancer serosal invasion: automated segmentation and multi-machine learning from two centers.

Journal of cancer research and clinical oncology
OBJECTIVE: The objective of this study is to develop an automated method for segmenting spleen computed tomography (CT) images using a deep learning model. This approach is intended to address the limitations of manual segmentation, which is known to...

Accelerating biopharmaceutical cell line selection with label-free multimodal nonlinear optical microscopy and machine learning.

Communications biology
The selection of high-performing cell lines is crucial for biopharmaceutical production but is often time-consuming and labor-intensive. We investigated label-free multimodal nonlinear optical microscopy for non-perturbative profiling of biopharmaceu...

Contrastive-learning of language embedding and biological features for cross modality encoding and effector prediction.

Nature communications
Identifying and characterizing virulence proteins secreted by Gram-negative bacteria are fundamental for deciphering microbial pathogenicity as well as aiding the development of therapeutic strategies. Effector predictors utilizing pre-trained protei...

A machine learning driven computationally efficient horse shoe shaped antenna design for internet of medical things.

PloS one
With bio-medical wearables becoming an essential part of Internet of Medical things (IoMT) for monitoring the health of workers, patients and others in different environments, antenna play a pivotal role in such wearables. In this communication, a no...

Evaluating the synergistic use of advanced liver models and AI for the prediction of drug-induced liver injury.

Expert opinion on drug metabolism & toxicology
INTRODUCTION: Drug-induced liver injury (DILI) is a leading cause of acute liver failure. Hepatotoxicity typically occurs only in a subset of individuals after prolonged exposure and constitutes a major risk factor for the termination of drug develop...

Integrating Machine Learning-Based Approaches into the Design of ASO Therapies.

Genes
Rare diseases impose a significant burden on affected individuals, caregivers, and healthcare systems worldwide. Developing effective therapeutics for these small patient populations presents substantial challenges. Antisense oligonucleotides (ASOs) ...

Application of machine learning for environmentally friendly advancement: exploring biomass-derived materials in wastewater treatment and agricultural sector - a review.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
There are several uses for biomass-derived materials (BDMs) in the irrigation and farming industries. To solve problems with material, process, and supply chain design, BDM systems have started to use machine learning (ML), a new technique approach. ...