Journal of chemical information and modeling
Jan 16, 2025
Designing chemically novel and synthesizable ligands from the largest possible chemical space is a major issue in modern drug discovery to identify early hits that are easily amenable to medicinal chemistry optimization. Starting from the sole three-...
In hospitals, timely interventions can prevent avoidable clinical deterioration. Early recognition of deterioration is vital to stopping further decline. Measuring the way patients position themselves in bed and change their positions may signal when...
International journal of molecular sciences
Jan 16, 2025
The COVID-19 pandemic has accelerated advances in molecular biology and virology, enabling the identification of key biomarkers to differentiate between severe and mild cases. Furthermore, the use of artificial intelligence (AI) and machine learning ...
Data scarcity in medical images makes transfer learning a common approach in computer-aided diagnosis. Some disease classification tasks can rely on large homogeneous public datasets to train the transferred model, while others cannot, i.e., endoscop...
BACKGROUND: Breast cancer screening plays a pivotal role in early detection and subsequent effective management of the disease, impacting patient outcomes and survival rates.
BACKGROUND: The two most commonly used methods to identify frailty are the frailty phenotype and the frailty index. However, both methods have limitations in clinical application. In addition, methods for measuring frailty have not yet been standardi...
The identification of significant predictors with higher model performance is the key objective in classification domain. A machine learning-based variable selection technique termed as CARS-Logistic model is proposed by coupling competitive adaptive...
OBJECTIVE: Non-puerperal mastitis (NPM) is an inflammatory breast disease affecting women during non-lactation periods, and it is prone to relapse after being cured. Accurate prediction of its recurrence is crucial for personalized adjuvant therapy, ...
Self-injury is common in all countries, and 20% of South Korean youths experience self-injury. One of the barriers to assessment and treatment planning is the tendency of young self-injurers to conceal their identities. Following a new stream of rese...
BACKGROUND: Bangladesh is facing a formidable challenge in mitigating waterborne diseases risk exacerbated by climate change. However, a comprehensive understanding of the spatio-temporal dynamics of these diseases at the district level remains elusi...
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