Computer methods and programs in biomedicine
Dec 18, 2024
OBJECTIVE: Social communication difficulties are a characteristic of autism spectrum disorder (ASD), a neurodevelopmental condition. The earlier method of diagnosing autism largely relied on error-prone behavioral observation of symptoms. More intell...
BACKGROUND: Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) in hypertrophic cardiomyopathy (HCM) typically represents myocardial fibrosis and may lead to fatal ventricular arrhythmias. However, CMR is resource-intensive and some...
BACKGROUND AND AIMS: An in silico quantitative score of coronary artery disease (ISCAD), built using machine learning and clinical data from electronic health records, has been shown to result in gradations of risk of subclinical atherosclerosis, cor...
AIMS: Atrial fibrillation (AF) is the most common sustained arrhythmia among patients with hypertrophic cardiomyopathy (HCM), leading to increased symptom burden and risk of thromboembolism. The HCM-AF score was developed to predict new-onset AF in p...
Cyclins are a group of proteins that regulate the cell cycle process by modulating various stages of cell division to ensure correct cell proliferation, differentiation, and apoptosis. Research on cyclins is crucial for understanding the biological f...
The lack of high-resolution, long-term PM observations in Greece and the Eastern Mediterranean hampers the development of spatial models that are crucial for providing representative exposure estimates to health studies. This work presents a spatial ...
SARS-CoV-2 has posed serious global health challenges not only because of the high degree of virus transmissibility but also due to its severe effects on the respiratory system, such as inducing changes in multiple organs through the ACE2 receptor. T...
Growing wildfire smoke represents a substantial threat to air quality and human health. However, the impact of wildfire smoke on human health remains imprecisely understood due to uncertainties in both the measurement of exposure of population to wil...
The outbreak of emerging acute viral diseases urgently requires the acceleration of specialized antiviral drug development, thus widely adopting phenotypic screening as a strategy for drug repurposing in antiviral research. However, traditional pheno...
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