AIMC Topic: Machine Learning

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Machine learning reveals the rules governing the efficacy of mesenchymal stromal cells in septic preclinical models.

Stem cell research & therapy
BACKGROUND: Mesenchymal Stromal Cells (MSCs) are the preferred candidates for therapeutics as they possess multi-directional differentiation potential, exhibit potent immunomodulatory activity, are anti-inflammatory, and can function like antimicrobi...

Development and validation of machine-learning models of diet management for hyperphenylalaninemia: a multicenter retrospective study.

BMC medicine
BACKGROUND: Assessing dietary phenylalanine (Phe) tolerance is crucial for managing hyperphenylalaninemia (HPA) in children. However, traditionally, adjusting the diet requires significant time from clinicians and parents. This study aims to investig...

Preventing illegal seafood trade using machine-learning assisted microbiome analysis.

BMC biology
BACKGROUND: Seafood is increasingly traded worldwide, but its supply chain is particularly prone to frauds. To increase consumer confidence, prevent illegal trade, and provide independent validation for eco-labelling, accurate tools for seafood trace...

On synergy between ultrahigh throughput screening and machine learning in biocatalyst engineering.

Faraday discussions
Protein design and directed evolution have separately contributed enormously to protein engineering. Without being mutually exclusive, the former relies on computation from first principles, while the latter is a combinatorial approach based on chanc...

Disease prediction with multi-omics and biomarkers empowers case-control genetic discoveries in the UK Biobank.

Nature genetics
The emergence of biobank-level datasets offers new opportunities to discover novel biomarkers and develop predictive algorithms for human disease. Here, we present an ensemble machine-learning framework (machine learning with phenotype associations, ...

Oscillations in an artificial neural network convert competing inputs into a temporal code.

PLoS computational biology
The field of computer vision has long drawn inspiration from neuroscientific studies of the human and non-human primate visual system. The development of convolutional neural networks (CNNs), for example, was informed by the properties of simple and ...

An intrusion detection model to detect zero-day attacks in unseen data using machine learning.

PloS one
In an era marked by pervasive digital connectivity, cybersecurity concerns have escalated. The rapid evolution of technology has led to a spectrum of cyber threats, including sophisticated zero-day attacks. This research addresses the challenge of ex...

Utility analysis and demonstration of real-world clinical texts: A case study on Japanese cancer-related EHRs.

PloS one
Real-world data (RWD) in the medical field, such as electronic health records (EHRs) and medication orders, are receiving increasing attention from researchers and practitioners. While structured data have played a vital role thus far, unstructured d...

A Predictive Model of Pressure Injury in Children Undergoing Living Donor Liver Transplantation Based on Machine Learning Algorithm.

Journal of advanced nursing
AIMS: The aim of our study was to formulate and validate a prediction model using machine learning algorithms to forecast the risk of pressure injuries (PIs) in children undergoing living donor liver transplantation (LDLT).

Sex-Specific Imaging Biomarkers for Parkinson's Disease Diagnosis: A Machine Learning Analysis.

Journal of imaging informatics in medicine
This study aimed to identify sex-specific imaging biomarkers for Parkinson's disease (PD) based on multiple MRI morphological features by using machine learning methods. Participants were categorized into female and male subgroups, and various struct...