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Machine learning-assisted screening of clinical features for predicting difficult-to-treat rheumatoid arthritis.

Scientific reports
To identify clinical features that predict the risk of meeting difficult-to-treat (D2T) rheumatoid arthritis (RA) definition in advance. This retrospective analysis included RA patients from the ATTRA registry who initiated biologic (b-) or targeted ...

Decision tree-based machine learning methods for identifying colorectal cancer-associated microRNA signatures and their regulatory networks.

Scientific reports
This study aimed to identify candidate diagnostic miRNAs from the serum of colorectal cancer (CRC) patients using Boruta, a wrapper-based feature selection technique, in combination with decision tree-based machine learning methods. We analyzed three...

The power of justifications to repair human-robot trust, even under moral disagreement.

Scientific reports
To avert criticism and losses of trust, robots that adopt social roles in the near future will have to be aware of and follow the norms of the communities in which they operate. However, norms often conflict with one another, and resolving such confl...

Reconfiguration of functional brain hierarchy in schizophrenia.

Translational psychiatry
The multidimensional nature of schizophrenia requires a comprehensive exploration of the functional and structural brain networks. While prior research has provided valuable insights into these aspects, our study goes a step further to investigate th...

Role of the rostral anterior cingulate cortex in emotion processing in Treatment Resistant Depression.

Translational psychiatry
The rostral anterior cingulate cortex (rACC) has been identified as a key region in treatment-resistant depression (TRD), potentially influencing the adaptive interplay between the default mode network and other critical neural networks. This study a...

Development and validation of diagnostic and prognostic prediction tools for dental caries in young children through prospective and cross-sectional observational studies: a protocol.

BMJ open
INTRODUCTION: Dental caries is the most common oral disease worldwide, affecting up to 90% of children globally. It can lead to pain, infection and impaired quality of life. Early prevention is a key strategy for reducing the prevalence of dental car...

Deep learning prediction of peak oxygen uptake in patients with coronary heart disease: a retrospective study.

BMJ open
OBJECTIVE: To develop and validate prediction models for peak oxygen uptake (VO₂peak) in patients with coronary heart disease (CHD) using submaximal cardiopulmonary exercise testing (CPET) indicators and deep learning methods.

Artificial neural networks as a prognostic tool using hyperspectral imaging on pretherapeutic histopathological specimens of esophageal adenocarcinoma.

Journal of cancer research and clinical oncology
PURPOSE: The integration of artificial intelligence (AI) with hyperspectral imaging (HSI) offers a promising avenue for improving pre-therapeutic prognosis, a key factor in optimizing cancer treatment strategies. This study explores the potential of ...

Predicting six-month mortality in adult hemophagocytic lymphohistiocytosis with machine learning: a prognostic approach utilizing laboratory data.

Annals of medicine
BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is associated with high mortality rates. This study was conducted to develop and validate a predictive model for adult HLH patients at high risk of six months mortality using machine learning (ML) ...

Explainable prediction of hypothermia risk in laparoscopic surgery: a retrospective cross-sectional study using machine learning.

BMC surgery
OBJECTIVE: This study aims to develop multiple machine learning models for predicting hypothermia risk in laparoscopic surgery and to perform interpretability analysis of the best-performing model. Our goal is to provide robust decision support for c...