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Prioritization of Mycotoxins Based on Their Genotoxic Potential with an In Silico-In Vitro Strategy.

Toxins
Humans are widely exposed to a great variety of mycotoxins and their mixtures. Therefore, it is important to design strategies that allow prioritizing mycotoxins based on their toxic potential in a time and cost-effective manner. A strategy combining...

PSA-Net: Deep learning-based physician style-aware segmentation network for postoperative prostate cancer clinical target volumes.

Artificial intelligence in medicine
PURPOSE: Automatic segmentation of medical images with deep learning (DL) algorithms has proven highly successful in recent times. With most of these automation networks, inter-observer variation is an acknowledged problem that leads to suboptimal re...

Early prediction of in-hospital death of COVID-19 patients: a machine-learning model based on age, blood analyses, and chest x-ray score.

eLife
An early-warning model to predict in-hospital mortality on admission of COVID-19 patients at an emergency department (ED) was developed and validated using a machine-learning model. In total, 2782 patients were enrolled between March 2020 and Decembe...

Diagnosis of Pituitary Adenoma Biopsies by Ultrahigh Resolution Optical Coherence Tomography Using Neuronal Networks.

Frontiers in endocrinology
OBJECTIVE: Despite advancements of intraoperative visualization, the difficulty to visually distinguish adenoma from adjacent pituitary gland due to textural similarities may lead to incomplete adenoma resection or impairment of pituitary function. T...

Natural language processing for cognitive therapy: Extracting schemas from thought records.

PloS one
The cognitive approach to psychotherapy aims to change patients' maladaptive schemas, that is, overly negative views on themselves, the world, or the future. To obtain awareness of these views, they record their thought processes in situations that c...

Predicting obesity and smoking using medication data: A machine-learning approach.

Pharmacoepidemiology and drug safety
PURPOSE: Administrative health datasets are widely used in public health research but often lack information about common confounders. We aimed to develop and validate machine learning (ML)-based models using medication data from Australia's Pharmace...

Classification of amyotrophic lateral sclerosis by brain volume, connectivity, and network dynamics.

Human brain mapping
Emerging studies corroborate the importance of neuroimaging biomarkers and machine learning to improve diagnostic classification of amyotrophic lateral sclerosis (ALS). While most studies focus on structural data, recent studies assessing functional ...

Early prediction of severe acute pancreatitis using machine learning.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
BACKGROUND: Acute pancreatitis (AP) is one of the most common causes of gastrointestinal-related hospitalizations in the United States. Severe AP (SAP) is associated with a mortality rate of nearly 30% and is distinguished from milder forms of AP. Ri...

Prediction of all-cause mortality in coronary artery disease patients with atrial fibrillation based on machine learning models.

BMC cardiovascular disorders
BACKGROUND: Machine learning (ML) can include more diverse and more complex variables to construct models. This study aimed to develop models based on ML methods to predict the all-cause mortality in coronary artery disease (CAD) patients with atrial...