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Functional dynamics between resident transcriptionally active microbes (TAMs) and host genes underlie Dengue severity.

PLoS neglected tropical diseases
Host-microbe interactions are increasingly recognized as an important module to understand disease progression and potential treatment strategies. Increasing evidence points to the microbiome's ability to modulate host gene expression, and thereby in...

Machine learning-based risk prediction model for cognitive dysfunction in elderly individuals.

PloS one
BACKGROUND: With the advancement of globalization, the prevalence of cognitive dysfunction in the elderly population has risen significantly. Early intervention may dramatically alleviate the disease burden and reduce economic costs associated with c...

Ethical compliance and institutional policy support for artificial intelligence integration in African TVET Education: A structural equation modeling approach.

PloS one
As artificial intelligence (AI) reshapes educational landscapes, ensuring ethical alignment and institutional responsiveness is essential particularly in skill-intensive sectors such as Technical and Vocational Education and Training (TVET). In this ...

A novel prognostic model for lung squamous cell carcinoma based on multi-omics analysis and machine learning.

PloS one
Lung squamous-cell carcinoma (LUSC) is a highly aggressive malignancy with a poor prognosis. Tertiary lymphoid structures (TLS) play a crucial role in the immune response and significantly influence the efficacy of immunotherapy. However, the prognos...

Exercise mitigates high-fat diet-induced cardiac dysfunction via APOE genotype- and immune-dependent mechanisms: A photon-counting CT study in adult mice.

PloS one
BACKGROUND: Cardiovascular dysfunction frequently accompanies aging and is often worsened by adverse lifestyle factors and genetic susceptibility. The apolipoprotein E (APOE) gene modulates susceptibility to cardiovascular disease, but how exercise a...

Leading predictors and their associations with combination opioid pain therapy in older adults with cancer: Application of machine learning approaches.

PloS one
Combined use of opioids and other pharmacological therapies used for pain management, such as non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, gabapentinoids, and/or skeletal muscle relaxants (SMRs), in older adult cancer survivors ca...

Using machine learning techniques for predicting the dropout of undergraduate students in Brazilian courses of statistics.

Anais da Academia Brasileira de Ciencias
This research aims to propose a machine learning approach to classify dropout outcomes among students in Statistics undergraduate programs in Brazil, identifying the most important factors associated with this phenomenon. This study uses microdata fr...

Association of Brain Age With Physical Disability and Cognitive Impairment in People With Multiple Sclerosis of the Same Age.

Neurology
BACKGROUND AND OBJECTIVES: The brain-predicted age difference (brain-PAD) is a novel marker of neurodegeneration in multiple sclerosis (MS). Brain-PAD has been associated with clinical disability in heterogeneous MS patient cohorts of varying ages an...

Comparison of machine learning classification and regression models for prediction of academic performance among postgraduate public health students.

Scientific reports
Machine learning (ML) is an artificial intelligence tool that focuses on learning by generating models using established algorithms that represent a given dataset. It can be used as a predictive tool for students' academic performance (AP) at both un...

Detection of cortical arousals in sleep using multimodal wearable sensors and machine learning.

Scientific reports
Cortical arousals are brief brain activations that disrupt sleep continuity and contribute to cardiovascular, cognitive, and behavioral impairments. Although polysomnography is the gold standard for arousal detection, its cost and complexity limit us...