Accurate molecular biomarker detection with digital-resolution sensitivity is essential for applications such as disease diagnostics, therapeutic studies, and biomedical research. Here, we present LOCA-PRAM (LOcalization with Context Awareness), a de...
This study presents an attractive single-component ratiometric fluorescent sensor that utilizes the oxidation of BSA-protected Au nanoclusters (BSA-Au NCs) by -Bromosuccinimide (NBS) to detect catecholamine neurotransmitters and their metabolites, wh...
Gold nanoparticles (GNPs), which appear red, are widely used as labels in lateral flow assays (LFAs) for visual detection. However, in blood-derived samples, hemolysis─caused by the rupture of red blood cells and the release of hemoglobin─creates a r...
This study introduces a fluorescence based sensing platform made to detect glial fibrillary acidic protein (GFAP), a critical biomarker associated with glioblastoma and other astrocytic malignancies. Leveraging the unique optical properties of copper...
Concerns regarding chronic injuries (e.g., fibrosis and carcinogenesis) induced by nanoparticles raised public health concerns and need to be rapidly assessed in hazard identification. Although in silico analysis is commonly used for risk assessment ...
To overcome the limitations of SERS in food safety monitoring, particularly significant interference from citrate ions, this study introduces an intelligent SERS-based platform for food safety monitoring. The platform utilizes sodium borohydride to a...
The detection and quantification of veterinary drug residues in meat remain a significant challenge due to the complex background interference inherent to the meat matrix, which compromises the stability and accuracy of spectroscopic analysis. This s...
BACKGROUND: Advances in bio-analyte detection demonstrate the need for innovation to overcome the limitations of traditional methods. Emerging viruses evolve into variants, driving the need for fast screening to minimize the time required for positiv...
Stroke affects approximately 12 million individuals annually, necessitating swift diagnosis to avert fatal outcomes. Current hospital imaging protocols often delay treatment, underscoring the need for portable diagnostic solutions. We have investigat...
Analytical methods : advancing methods and applications
Feb 20, 2025
Ensuring food safety necessitates rapid identification of pesticide residues on fruits. Herein, we developed a shape-adaptable flexible surface-enhanced Raman scattering (SERS) substrate, combined with a deep learning algorithm, to quickly detect and...
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