AIMC Topic: Middle Aged

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Natural language processing assisted detection of inappropriate proton pump inhibitor use in adult hospitalised patients.

European journal of hospital pharmacy : science and practice
OBJECTIVES: To establish a clinical application monitoring system for proton pump inhibitors (PPI-MS) and to enhance the detection and intervention of inappropriate PPI use in adult hospitalised patients.

Predicting knee osteoarthritis progression using neural network with longitudinal MRI radiomics, and biochemical biomarkers: A modeling study.

PLoS medicine
BACKGROUND: Knee osteoarthritis (KOA) worsens both structurally and symptomatically, yet no model predicts KOA progression using Magnetic Resonance Image (MRI) radiomics and biomarkers. This study aimed to develop and test the longitudinal Load-Beari...

The additive effect of the estimated glucose disposal rate and a body shape index on cardiovascular disease: A cross-sectional study.

PloS one
BACKGROUND: The glucose disposal rate (eGDR) and a body shape index (ABSI) are predictors strongly associated with cardiovascular disease (CVD) and outcomes. However, whether they have additive effects on CVD risk is unknown. This study aimed to inve...

Multi-task deep learning for predicting metabolic syndrome from retinal fundus images in a Japanese health checkup dataset.

PloS one
BACKGROUND: Retinal fundus images provide a noninvasive window into systemic health, offering opportunities for early detection of metabolic disorders such as metabolic syndrome (METS).

A hybrid approach for forecasting peak expiratory flow rate in asthma patients using combined linear regression and random forest model.

PloS one
Asthma is a frequent and long-lasting disorder associated with airway inflammation. The disease severity may lead to serious health concerns and even mortality. In this work, we propose a novel hybrid approach using machine learning models and simila...

External validation of precisebreast, a digital prognostic test for predicting breast cancer recurrence, in an early-stage cohort from the Netherlands.

Breast cancer research : BCR
BACKGROUND: Current clinical guidelines recommend gene expression profiling to guide treatment in early-stage breast cancer. PreciseBreast (PDxBR) is a digital prognostic tool that integrates artificial intelligence (AI)-derived features from hematox...

AI-assisted 3D versus conventional 2D preoperative planning in total hip arthroplasty for Crowe type II-IV high hip dislocation: a two-year retrospective study.

Journal of orthopaedic surgery and research
BACKGROUND: With the growing complexity of total hip arthroplasty (THA) for high hip dislocation (HHD), artificial intelligence (AI)-assisted three-dimensional (3D) preoperative planning has emerged as a promising tool to enhance surgical accuracy. T...

Machine learning-assisted radiogenomic analysis for miR-15a expression prediction in renal cell carcinoma.

BMC cancer
BACKGROUND: Renal cell carcinoma (RCC) is a prevalent malignancy with highly variable outcomes. MicroRNA-15a (miR-15a) has emerged as a promising prognostic biomarker in RCC, linked to angiogenesis, apoptosis, and proliferation. Radiogenomics integra...

A development of machine learning models to preoperatively predict insufficient clinical improvement after total knee arthroplasty.

Journal of orthopaedic surgery and research
BACKGROUND: Identifying patients unlikely to achieve meaningful improvement following total knee arthroplasty (TKA) supports more effective shared decision-making (SDM). This study aimed to develop and validate machine learning (ML) models that preop...